Biochemical characterization of the virus causing leukoencephalitis and arthritis in goats

J. E. Clements, O. Narayan, L. C. Cork

Research output: Contribution to journalArticlepeer-review

Abstract

Goat leukoencephalitis-arthritis virus (GLV) has the density of a retrovirus in sucrose and contains an endogenous RNA-dependent DNA polymerase (reverse transcriptase). The virion reverse transcriptase virus the synthetic RNA template poly(rA).(dT)12 but not the synthetic DNA template poly(dA).(dT)12. A high mol. wt. RNA similar in size to visna virs RNA was isolated from 3H-uridine-labelled virions. The major structural protein of GLV has the same mol. wt. as that of visna virus. From these data the GLV appears to be a retrovirus.

Original languageEnglish (US)
Pages (from-to)423-427
Number of pages5
JournalJournal of General Virology
Volume50
Issue number2
DOIs
StatePublished - 1980

ASJC Scopus subject areas

  • Virology

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