@article{35a4f83cb95f4bd09736e09c16d2ab00,
title = "Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells",
abstract = "We provide direct evidence that Bin/Amphiphysin/Rvs (BAR) family members bend the steady state membrane architecture of organelles in intact cells. In response to inducible BAR molecular actuators, organelles exhibit distinct changes to the orientation and degree of their membrane curvature. This rapidly inducible system may offer a mechanism by which to better understand the structure-function relationship of intracellular organelles.",
author = "Allison Suarez and Tasuku Ueno and Robert Huebner and McCaffery, {J. Michael} and Takanari Inoue",
note = "Funding Information: We are grateful for the constructs encoding human Amphiphysin 1 N-BAR and human FBP17 F-BAR from Dr. Toshiki Itoh (Kobe University), and human MIM I-BAR from Dr. Pekka Lappalainen (University of Helsinki). We also extend our gratitude to Dr. T. Komatsu, R. DeRose, and T. Sharma for constructive comments on the manuscript. This study was supported in part by the National Institute of Health (NIH) (GM092930 to T.I.) and by JST (10216 to T.I.).",
year = "2014",
month = may,
day = "6",
doi = "10.1038/srep04693",
language = "English (US)",
volume = "4",
journal = "Scientific reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
}