Fecal and urinary urobilinogen excretion levels were determined in normal, healthy, mongrel dogs. Unlike the human, in the dog most of the theoretical daily production of bile pigment can be recovered in the feces and urine. Following ligation of the common bile duct and cholecystectomy, it was observed that the dogs became jaundiced but maintained serum bilirubin levels in a relatively low range (4 to 8 mg. per cent). Unlike the human with complete biliary obstruction, the dogs excreted their presumed daily production of bilirubin in the urine, thus accounting for the low serum levels.
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