Bilateral putaminal hemorrhages: Serious complication of methanol intoxication

Nitipong Permpalung, Wisit Cheungpasitporn, Daych Chongnarungsin, Travis M. Hodgdon

Research output: Contribution to journalArticlepeer-review


Context: Methanol intoxication is a life-threatening condition. Hallmark of clinical presentations include severe wide anion gap metabolic acidosis with very high serum osmolar gap and visual complication. Case Report: We report a case of severe methanol intoxication with bilateral putaminal hemorrhage, an uncommon serious complication. A 56-year-old man presented with altered mental status. Fundus examination showed optic disc edema. Arterial Blood Gas (ABG) revealed severe anion gap metabolic acidosis with osmolal gap. Head computed tomography (CT) showed hypodense lesions in basal ganglia bilaterally. Hemodialysis and intravenous fomepizole were initiated. Serum methanol level was significantly elevated. Unfortunately, patient was lethargic 2 weeks after discharge. Repeated CT of head demonstrated new putaminal hemorrhages. Conclusion: Bilateral putaminal hemorrhage is an uncommon but serious complication in methanol intoxication. Clinicians should have high index of suspicion for putaminal hemorrhage when patients with recent methanol intoxication present with altered mental status.

Original languageEnglish (US)
Pages (from-to)623-624
Number of pages2
JournalNorth American Journal of Medical Sciences
Issue number10
StatePublished - Oct 2013
Externally publishedYes


  • Basal ganglion hemorrhage
  • Metabolic acidosis
  • Methanol intoxication
  • Putaminal hemorrhage

ASJC Scopus subject areas

  • Medicine(all)


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