Bifurcation Scenarios of a Modified Mathematical Model for Intracellular Ca2+ Oscillations

Quan Bao Ji, Yi Zhou, Zhuo Qin Yang, Xiang Ying Meng

Research output: Contribution to journalArticlepeer-review

Abstract

The contribution of this work is the modification of a mathematical model for bursting Ca2+ oscillations by introducing the proportion of receptors not inactivated by Ca2+ as a new variable. Generation mechanisms of different oscillatory patterns in this modified model are investigated and classified, based on fast/slow dynamical analysis. It is shown that periodic oscillations appear around the original chaotic regions. Moreover, two new types of oscillatory phenomena are observed at the sustaining region. The results may be instructive for understanding the difference between direct observation of dynamical behavior in real cells and theoretical explanations under a variety of stimulus conditions.

Original languageEnglish (US)
Article number050501
JournalChinese Physics Letters
Volume32
Issue number5
DOIs
StatePublished - May 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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