Bifid tongue: A rare feature associated with infants of diabetic mother syndrome

Aaron James, Kathy Culver, Bryan Hall, Mahin Golabi

Research output: Contribution to journalArticle

Abstract

Infants born to diabetic mothers (IDM) are well documented to have a higher rate of congenital malformations. Sacral agenesis/hypogenesis and caudal dysgenesis are classically linked to maternal diabetes, but many other types of anomalies are more frequent. In this case report, we describe a male infant born to a diabetic mother who in addition to other typical congenital abnormalities was born with an impressive bifid tongue. Accompanying congenital anomalies include unilateral microphthalmia, bilateral microtia, cleft palate, micropenis with unilateral cryptorchidism, bilateral radial hypoplasia, unilateral pre-axial Polydactyly, and mid-line central nervous system defects including arhinencephaly and pituitary hypoplasia. Review of the literature reveals an additional case of an infant with a bifid tongue born to a diabetic mother [Comess et al., 1969]. In conclusion, bifid tongue without oral hamartoma, a rare congenital anomaly, can be an associated finding in IDM.

Original languageEnglish (US)
Pages (from-to)2035-2039
Number of pages5
JournalAmerican Journal of Medical Genetics, Part A
Volume143
Issue number17
DOIs
StatePublished - Sep 1 2007
Externally publishedYes

Fingerprint

Tongue
Mothers
Holoprosencephaly
Microphthalmos
Polydactyly
Cryptorchidism
Hamartoma
Cleft Palate
Central Nervous System

Keywords

  • Bifid tongue
  • Gestational diabetes
  • Infants of diabetic mother syndrome
  • Oculoauriculovertebral anomalies
  • Pregnancy in diabetics

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Bifid tongue : A rare feature associated with infants of diabetic mother syndrome. / James, Aaron; Culver, Kathy; Hall, Bryan; Golabi, Mahin.

In: American Journal of Medical Genetics, Part A, Vol. 143, No. 17, 01.09.2007, p. 2035-2039.

Research output: Contribution to journalArticle

James, Aaron ; Culver, Kathy ; Hall, Bryan ; Golabi, Mahin. / Bifid tongue : A rare feature associated with infants of diabetic mother syndrome. In: American Journal of Medical Genetics, Part A. 2007 ; Vol. 143, No. 17. pp. 2035-2039.
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