Bi-exponential T2 decay in dairy cream phantoms

Craig Jones; Alex MacKay; Brian Rutt

doi:10.1016/S0730-725X(97)00250-6

Bi-exponential T₂ decay in dairy cream phantoms

Craig Jones, Alex MacKay, Brian Rutt

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

MRI phantoms are an important part of any experiment because they provide a reference of known parameters. There are many choices of mono- exponential T₂ phantoms, but few choices for bi-exponential T₂ phantoms. We have found that dairy cream provides an excellent bi-exponential T₂ model with similar relaxation times to those found in white matter. Five cream phantoms of different milk fat percentages (2, 6, 10, 18 and 35%) were imaged with an optimized Carr-Purcell-Meiboom-Gill sequence. The decay curves for each of the phantoms were fit using Non-Negative Least Squares. We found that the short T₂ component fraction relative to the total energy in the distribution correlated linearly (r = 0.9973) with the milk fat percentage. The short T₂ time was 38 ± 4 ms and the long T₂ time was 135 ± 4 ms.

Original language	English (US)
Pages (from-to)	83-85
Number of pages	3
Journal	Magnetic Resonance Imaging
Volume	16
Issue number	1
DOIs	https://doi.org/10.1016/S0730-725X(97)00250-6
State	Published - Jan 1998
Externally published	Yes

Keywords

Bi-exponential T decay
Myelin
Phantom
T relaxation

ASJC Scopus subject areas

Biophysics
Biomedical Engineering
Radiology Nuclear Medicine and imaging

Access to Document

10.1016/S0730-725X(97)00250-6

Cite this

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title = "Bi-exponential T2 decay in dairy cream phantoms",

abstract = "MRI phantoms are an important part of any experiment because they provide a reference of known parameters. There are many choices of mono- exponential T2 phantoms, but few choices for bi-exponential T2 phantoms. We have found that dairy cream provides an excellent bi-exponential T2 model with similar relaxation times to those found in white matter. Five cream phantoms of different milk fat percentages (2, 6, 10, 18 and 35%) were imaged with an optimized Carr-Purcell-Meiboom-Gill sequence. The decay curves for each of the phantoms were fit using Non-Negative Least Squares. We found that the short T2 component fraction relative to the total energy in the distribution correlated linearly (r = 0.9973) with the milk fat percentage. The short T2 time was 38 ± 4 ms and the long T2 time was 135 ± 4 ms.",

keywords = "Bi-exponential T decay, Myelin, Phantom, T relaxation",

author = "Craig Jones and Alex MacKay and Brian Rutt",

note = "Funding Information: Acknowledgements—We wish to thank Ken Chu for the idea of using dairy cream as a bi-exponential T 2 phantom. We also wish to thank the Multiple Sclerosis Society of Canada for their financial support.",

year = "1998",

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T1 - Bi-exponential T2 decay in dairy cream phantoms

AU - Jones, Craig

AU - MacKay, Alex

AU - Rutt, Brian

N1 - Funding Information: Acknowledgements—We wish to thank Ken Chu for the idea of using dairy cream as a bi-exponential T 2 phantom. We also wish to thank the Multiple Sclerosis Society of Canada for their financial support.

PY - 1998/1

Y1 - 1998/1

N2 - MRI phantoms are an important part of any experiment because they provide a reference of known parameters. There are many choices of mono- exponential T2 phantoms, but few choices for bi-exponential T2 phantoms. We have found that dairy cream provides an excellent bi-exponential T2 model with similar relaxation times to those found in white matter. Five cream phantoms of different milk fat percentages (2, 6, 10, 18 and 35%) were imaged with an optimized Carr-Purcell-Meiboom-Gill sequence. The decay curves for each of the phantoms were fit using Non-Negative Least Squares. We found that the short T2 component fraction relative to the total energy in the distribution correlated linearly (r = 0.9973) with the milk fat percentage. The short T2 time was 38 ± 4 ms and the long T2 time was 135 ± 4 ms.

AB - MRI phantoms are an important part of any experiment because they provide a reference of known parameters. There are many choices of mono- exponential T2 phantoms, but few choices for bi-exponential T2 phantoms. We have found that dairy cream provides an excellent bi-exponential T2 model with similar relaxation times to those found in white matter. Five cream phantoms of different milk fat percentages (2, 6, 10, 18 and 35%) were imaged with an optimized Carr-Purcell-Meiboom-Gill sequence. The decay curves for each of the phantoms were fit using Non-Negative Least Squares. We found that the short T2 component fraction relative to the total energy in the distribution correlated linearly (r = 0.9973) with the milk fat percentage. The short T2 time was 38 ± 4 ms and the long T2 time was 135 ± 4 ms.

KW - Bi-exponential T decay

KW - Myelin

KW - Phantom

KW - T relaxation

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