Beyond Genetics: Surprising Determinants of Cell Fate in Antitumor Drugs

Andrew J. Holland; Don W. Cleveland

doi:10.1016/j.ccr.2008.07.010

Beyond Genetics: Surprising Determinants of Cell Fate in Antitumor Drugs

Andrew J. Holland, Don W. Cleveland

Research output: Contribution to journal › Short survey › peer-review

9 Scopus citations

Abstract

In this issue of Cancer Cell, Gascoigne and Taylor (2008) report their findings of following 10,000 single cells incubated with three classes of antimitotic drugs, including paclitaxel (taxol). This extensive analysis reveals a previously unappreciated complexity in response to such drugs and demonstrates that it is more than genetics that determines cell life or death.

Original language	English (US)
Pages (from-to)	103-105
Number of pages	3
Journal	Cancer cell
Volume	14
Issue number	2
DOIs	https://doi.org/10.1016/j.ccr.2008.07.010
State	Published - Aug 12 2008
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cell Biology
Cancer Research

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10.1016/j.ccr.2008.07.010

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title = "Beyond Genetics: Surprising Determinants of Cell Fate in Antitumor Drugs",

abstract = "In this issue of Cancer Cell, Gascoigne and Taylor (2008) report their findings of following 10,000 single cells incubated with three classes of antimitotic drugs, including paclitaxel (taxol). This extensive analysis reveals a previously unappreciated complexity in response to such drugs and demonstrates that it is more than genetics that determines cell life or death.",

author = "Holland, {Andrew J.} and Cleveland, {Don W.}",

year = "2008",

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T1 - Beyond Genetics

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AU - Holland, Andrew J.

AU - Cleveland, Don W.

PY - 2008/8/12

Y1 - 2008/8/12

N2 - In this issue of Cancer Cell, Gascoigne and Taylor (2008) report their findings of following 10,000 single cells incubated with three classes of antimitotic drugs, including paclitaxel (taxol). This extensive analysis reveals a previously unappreciated complexity in response to such drugs and demonstrates that it is more than genetics that determines cell life or death.

AB - In this issue of Cancer Cell, Gascoigne and Taylor (2008) report their findings of following 10,000 single cells incubated with three classes of antimitotic drugs, including paclitaxel (taxol). This extensive analysis reveals a previously unappreciated complexity in response to such drugs and demonstrates that it is more than genetics that determines cell life or death.

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DO - 10.1016/j.ccr.2008.07.010

M3 - Short survey

C2 - 18691543

AN - SCOPUS:48449086954

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JO - Cancer cell

JF - Cancer cell

IS - 2

ER -

Beyond Genetics: Surprising Determinants of Cell Fate in Antitumor Drugs

Abstract

ASJC Scopus subject areas

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