Beyond Genetics: Surprising Determinants of Cell Fate in Antitumor Drugs

Andrew J. Holland, Don W. Cleveland

Research output: Contribution to journalShort survey

Abstract

In this issue of Cancer Cell, Gascoigne and Taylor (2008) report their findings of following 10,000 single cells incubated with three classes of antimitotic drugs, including paclitaxel (taxol). This extensive analysis reveals a previously unappreciated complexity in response to such drugs and demonstrates that it is more than genetics that determines cell life or death.

Original languageEnglish (US)
Pages (from-to)103-105
Number of pages3
JournalCancer cell
Volume14
Issue number2
DOIs
StatePublished - Aug 12 2008
Externally publishedYes

ASJC Scopus subject areas

  • Oncology
  • Cell Biology
  • Cancer Research

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