Beyond gastric emptying: A "toxic" lesson about gastroparesis

Research output: Contribution to journalReview articlepeer-review


The first published controlled trial of intrapyloric botulinum toxin for gastroparesis failed to demonstrate a significant effect of treatment on symptoms, despite an improvement in gastric emptying. In this editorial, I discuss the limitations and implications of this study, with particular emphasis on what the use of botulinum toxin can teach us about the pathophysiology of gastroparesis and other gastrointestinal smooth muscle disorders.

Original languageEnglish (US)
Pages (from-to)424-426
Number of pages3
JournalAmerican Journal of Gastroenterology
Issue number2
StatePublished - Feb 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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