Beta/Gamma EEG activity in patients with primary and secondary insomnia and good sleeper controls

M. L. Perlis, Michael T Smith, P. J. Andrews, H. Orff, D. E. Giles

Research output: Contribution to journalArticle

Abstract

Study Objective: Several studies have shown that patients with insomnia exhibit elevated levels of Beta EEG activity (14-35 Hz) at or around sleep onset and during NREM sleep. In this study, we evaluated 1) the extent to which high frequency EEG activity is limited to the 14-32 Hz domain, 2) whether high frequency EEG activity (HFA) is associated with discrepancies between subjective and PSG measures of sleep continuity, and 3) the extent to which high frequency EEG activity occurs in patients with primary, as opposed to secondary, insomnia. Design: Three groups (n=9 per group) were compared: Primary Insomnia, Insomnia secondary to Major Depression, and Good Sleeper Controls. Groups were matched for age, sex and body mass. Average spectral profiles were created for each NREM cycle after removing waking and movement epochs and epochs containing micro- or mini-arousals. Setting: Sleep Research Laboratory Patients or Participants: Patients with primary and secondary insomnia interventions: N/A Measurements and Results: Subjects with Primary Insomnia exhibited more average NREM activity for Beta-1 (14-20Hz), Beta-2 (20-35Hz) and Gamma activity (35-45Hz) than the other two groups (p.

Original languageEnglish (US)
Pages (from-to)110-117
Number of pages8
JournalSleep
Volume24
Issue number1
StatePublished - Feb 1 2001
Externally publishedYes

Fingerprint

Sleep Initiation and Maintenance Disorders
Electroencephalography
Sleep
Arousal
Research Design
Depression
Research

Keywords

  • Beta
  • High frequency EEG
  • Insomnia
  • Power spectral analyses
  • Sleep

ASJC Scopus subject areas

  • Physiology

Cite this

Perlis, M. L., Smith, M. T., Andrews, P. J., Orff, H., & Giles, D. E. (2001). Beta/Gamma EEG activity in patients with primary and secondary insomnia and good sleeper controls. Sleep, 24(1), 110-117.

Beta/Gamma EEG activity in patients with primary and secondary insomnia and good sleeper controls. / Perlis, M. L.; Smith, Michael T; Andrews, P. J.; Orff, H.; Giles, D. E.

In: Sleep, Vol. 24, No. 1, 01.02.2001, p. 110-117.

Research output: Contribution to journalArticle

Perlis, ML, Smith, MT, Andrews, PJ, Orff, H & Giles, DE 2001, 'Beta/Gamma EEG activity in patients with primary and secondary insomnia and good sleeper controls', Sleep, vol. 24, no. 1, pp. 110-117.
Perlis, M. L. ; Smith, Michael T ; Andrews, P. J. ; Orff, H. ; Giles, D. E. / Beta/Gamma EEG activity in patients with primary and secondary insomnia and good sleeper controls. In: Sleep. 2001 ; Vol. 24, No. 1. pp. 110-117.
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