Beta-carotene increases lung cancer incidence in cigarette smokers

Luigi M. De Luca, Sharon A. Ross

Research output: Contribution to journalShort surveypeer-review


Clinical trials were designed to validate the protective effect of β-carotene in populations of cigarette smokers at high risk for lung cancer development. Strikingly, an increase in lung cancer resulted following β-carotene supplementation in two separate studies in Finland and the United States. These trials were conducted without any evidence that β-carotene prevents lung cancer in animal models.

Original languageEnglish (US)
Pages (from-to)178-180
Number of pages3
JournalNutrition reviews
Issue number6
StatePublished - Jun 1996
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics


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