Beta blockers as anti-arrhythmic agents

Daejoon Anh, Joseph Marine

Research output: Contribution to journalArticle

Abstract

Although beta-adrenergic blocking agents are not always considered anti-arrhythmic drugs, the results of several recent trials have suggested an anti-arrhythmic mechanism for at least part of their mortality benefit in the treatment of chronic congestive heart failure. We review background experimental and clinical evidence for the anti-arrhythmic actions of beta-blockers and then review the results of published beta-blocker heart failure trials. A majority of trials showed improvement in overall survival as well as reduction in sudden death and ventricular arrhythmias with beta-blocker treatment. Although different effects were seen with different specific agents, these trials overall support a clinically significant anti-arrhythmic effect of several beta-blockers.

Original languageEnglish (US)
Pages (from-to)139-147
Number of pages9
JournalHeart Failure Reviews
Volume9
Issue number2
DOIs
StatePublished - Apr 2004

Fingerprint

Anti-Arrhythmia Agents
Heart Failure
Adrenergic beta-Antagonists
Sudden Death
Cardiac Arrhythmias
Mortality
Pharmaceutical Preparations

Keywords

  • Adrenergic beta-antagonists
  • Anti-arrhythmia agents
  • Cardiac
  • Death
  • Sudden
  • Tachycardia
  • Ventricular
  • Ventricular fibrillation

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Beta blockers as anti-arrhythmic agents. / Anh, Daejoon; Marine, Joseph.

In: Heart Failure Reviews, Vol. 9, No. 2, 04.2004, p. 139-147.

Research output: Contribution to journalArticle

Anh, Daejoon ; Marine, Joseph. / Beta blockers as anti-arrhythmic agents. In: Heart Failure Reviews. 2004 ; Vol. 9, No. 2. pp. 139-147.
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