Beta-aminoaciduria in patients with burkitt’s lymphomal

T. Phillip Waalkes, Charles W. Gehrke, Duane B. Lakings, Robert W. Zumwalt, Kenneth C. Kuo, Samuel A. Jacobs, Ernest Borek

Research output: Contribution to journalArticlepeer-review

Abstract

The massive amounts of β-aminoisobutyric acid (β-AIBA) in the urine of Burkitt’s lymphoma patients were measured along with other α-amino acids and β-alanine present in normal and decreased levels. The ratios of the amount of β-AIBA to β-alanine, in µmoles/kg urine collected in 24 hours, were elevated for all patients. The degree of elevation of β-AIBA excretion and the ratio of the two p-amino acids appeared to be related to the amount of tumor mass present. These analyses may have possible value in monitoring patients with Burkitt’s lymphoma during their disease course.

Original languageEnglish (US)
Pages (from-to)435-438
Number of pages4
JournalJournal of the National Cancer Institute
Volume57
Issue number2
DOIs
StatePublished - 1976

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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