Abstract
The massive amounts of β-aminoisobutyric acid (β-AIBA) in the urine of Burkitt’s lymphoma patients were measured along with other α-amino acids and β-alanine present in normal and decreased levels. The ratios of the amount of β-AIBA to β-alanine, in µmoles/kg urine collected in 24 hours, were elevated for all patients. The degree of elevation of β-AIBA excretion and the ratio of the two p-amino acids appeared to be related to the amount of tumor mass present. These analyses may have possible value in monitoring patients with Burkitt’s lymphoma during their disease course.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 435-438 |
| Number of pages | 4 |
| Journal | Journal of the National Cancer Institute |
| Volume | 57 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1976 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cancer Research
- Oncology
Cite this
Beta-aminoaciduria in patients with burkitt’s lymphomal. / Waalkes, T. Phillip; Gehrke, Charles W.; Lakings, Duane B.; Zumwalt, Robert W.; Kuo, Kenneth C.; Jacobs, Samuel A.; Borek, Ernest.
In: Journal of the National Cancer Institute, Vol. 57, No. 2, 1976, p. 435-438.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Beta-aminoaciduria in patients with burkitt’s lymphomal
AU - Waalkes, T. Phillip
AU - Gehrke, Charles W.
AU - Lakings, Duane B.
AU - Zumwalt, Robert W.
AU - Kuo, Kenneth C.
AU - Jacobs, Samuel A.
AU - Borek, Ernest
PY - 1976
Y1 - 1976
N2 - The massive amounts of β-aminoisobutyric acid (β-AIBA) in the urine of Burkitt’s lymphoma patients were measured along with other α-amino acids and β-alanine present in normal and decreased levels. The ratios of the amount of β-AIBA to β-alanine, in µmoles/kg urine collected in 24 hours, were elevated for all patients. The degree of elevation of β-AIBA excretion and the ratio of the two p-amino acids appeared to be related to the amount of tumor mass present. These analyses may have possible value in monitoring patients with Burkitt’s lymphoma during their disease course.
AB - The massive amounts of β-aminoisobutyric acid (β-AIBA) in the urine of Burkitt’s lymphoma patients were measured along with other α-amino acids and β-alanine present in normal and decreased levels. The ratios of the amount of β-AIBA to β-alanine, in µmoles/kg urine collected in 24 hours, were elevated for all patients. The degree of elevation of β-AIBA excretion and the ratio of the two p-amino acids appeared to be related to the amount of tumor mass present. These analyses may have possible value in monitoring patients with Burkitt’s lymphoma during their disease course.
UR - http://www.scopus.com/inward/record.url?scp=0017147441&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0017147441&partnerID=8YFLogxK
U2 - 10.1093/jnci/57.2.435
DO - 10.1093/jnci/57.2.435
M3 - Article
C2 - 1003521
AN - SCOPUS:0017147441
VL - 57
SP - 435
EP - 438
JO - Journal of the National Cancer Institute
JF - Journal of the National Cancer Institute
SN - 0027-8874
IS - 2
ER -