Benign lesions of the mediastinum: A review with emphasis on cytology and small biopsy specimens

Brian D. Stewart, Christopher J. VandenBussche, Marino E. Leon

Research output: Contribution to journalArticlepeer-review

Abstract

This review focuses on the diagnosis of select benign processes, ranging from reactive entities to heterotopic tissues to neoplasms, which may occur in the mediastinum. Currently, the mediastinum can be evaluated and biopsied with endoscopic procedures. Therefore, cytopathology specimens, fine needle aspirations, and small biopsies play an important role in the diagnosis of these lesions. In this review, an emphasis is given to relevant clinical presentations, histologic and cytologic findings, differential diagnoses, ancillary testing, and interpretation. Pitfalls are reviewed and discussed in each section. It is important for both surgical pathologists and cytopathologists to be familiar with these entities and their cytologic and histologic features that may be helpful in reaching a diagnosis.

Original languageEnglish (US)
Pages (from-to)199-210
Number of pages12
JournalSeminars in Diagnostic Pathology
Volume37
Issue number4
DOIs
StatePublished - Jul 2020

Keywords

  • Bronchogenic cyst
  • Duplication cyst
  • Ectopic parathyroid
  • Ectopic salivary gland
  • Ectopic sebaceous
  • Ectopic thyroid
  • Foregut cyst
  • Hemangioma
  • Lymphangioma
  • Mediastinum
  • Müllerian cyst
  • Paraganglioma
  • Parathyroid
  • Pericardial cyst
  • Solitary fibrous tumor
  • Thymolipoma

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Fingerprint Dive into the research topics of 'Benign lesions of the mediastinum: A review with emphasis on cytology and small biopsy specimens'. Together they form a unique fingerprint.

Cite this