Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder

Monique Ernst, David A. Luckenbaugh, Eric T. Moolchan, Michelle K. Leff, Rachel Allen, Neir Eshela, Edythe D. London, Alane Kimes

Research output: Contribution to journalArticle

Abstract

OBJECTIVE. Our goal was to examine substance-use initiation in healthy adolescents and in adolescents who have been diagnosed with attention-deficit/ hyperactivity disorder. METHODS. Seventy-eight adolescents (28 healthy and 50 with attention-deficit/hyperactivity disorder) participated in an ongoing longitudinal study of predictors of substance use. The substances most commonly reported were tobacco, alcohol, and marijuana. Aggression, conduct problems, hyperactivity, impulsivity, inattention, anxiety/depression, social difficulties, and somatic complaints were assessed at study entry and tested as predictors for later substance use. RESULTS. With an average of 4 years into the study, 37 adolescents had not used any substances, 41 had experimented with at least 1 substance, and 29 experimented with >1 substance. Psychiatric diagnoses (attention-deficit/hyperactivity disorder, attention-deficit/ hyperactivity disorder and conduct disorder, and attention-deficit/hyperactivity disorder and depression/anxiety) did not influence reports of substance use. Distinct behavioral measures collected at study entry predicted use of different substances. In a multivariate analysis, aggression had the greatest association with tobacco smoking and marijuana use. Impulsivity was associated with alcohol use. Severity of drug exposure, indexed by the number of substances used, was predicted by aggression. CONCLUSIONS. This 4-year longitudinal study captured the onset of substance use, not abuse. Behavioral predictors differed with the type of substance used. These behavioral characteristics may raise suspicion among pediatricians for enhanced risk for substance-use initiation.

Original languageEnglish (US)
Pages (from-to)2030-2039
Number of pages10
JournalPediatrics
Volume117
Issue number6
DOIs
StatePublished - Jun 2006
Externally publishedYes

Fingerprint

Attention Deficit Disorder with Hyperactivity
Aggression
Impulsive Behavior
Cannabis
Longitudinal Studies
Anxiety
Alcohols
Depression
Conduct Disorder
Mental Disorders
Tobacco
Multivariate Analysis
Smoking
Pharmaceutical Preparations

Keywords

  • Aggression
  • Alcohol
  • Conduct disorder
  • Experimentation
  • Externalizing behavior disorders
  • Impulsivity
  • Marijuana
  • Tobacco

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Ernst, M., Luckenbaugh, D. A., Moolchan, E. T., Leff, M. K., Allen, R., Eshela, N., ... Kimes, A. (2006). Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder. Pediatrics, 117(6), 2030-2039. https://doi.org/10.1542/peds.2005-0704

Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder. / Ernst, Monique; Luckenbaugh, David A.; Moolchan, Eric T.; Leff, Michelle K.; Allen, Rachel; Eshela, Neir; London, Edythe D.; Kimes, Alane.

In: Pediatrics, Vol. 117, No. 6, 06.2006, p. 2030-2039.

Research output: Contribution to journalArticle

Ernst, M, Luckenbaugh, DA, Moolchan, ET, Leff, MK, Allen, R, Eshela, N, London, ED & Kimes, A 2006, 'Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder', Pediatrics, vol. 117, no. 6, pp. 2030-2039. https://doi.org/10.1542/peds.2005-0704
Ernst, Monique ; Luckenbaugh, David A. ; Moolchan, Eric T. ; Leff, Michelle K. ; Allen, Rachel ; Eshela, Neir ; London, Edythe D. ; Kimes, Alane. / Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder. In: Pediatrics. 2006 ; Vol. 117, No. 6. pp. 2030-2039.
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