Behavioral effects of morphine and methadone in rhesus monkeys

George Bigelow, Travis Thompson

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Two rhesus monkeys, working on fixed-ratio schedules for appetitive reinforcement, were given injections of morphine sulfate and methadone hydrochloride. Morphine was the more potent in decreasing operant responding. Responding was restored sooner following methadone injections than following morphine injections. Response-decreasing potency does not correspond to analgesic potency.

Original languageEnglish (US)
Pages (from-to)215-217
Number of pages3
JournalPsychonomic Science
Issue number5
StatePublished - May 1971
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)


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