Behavioral change in a cancer patient following intrathecal β-endorphin administration

D. Pickar, M. Dubois, M. R. Cohen

Research output: Contribution to journalArticle


A patient with disseminated malignancy received 3 mg of synthetic β-endorphin administered intrathecally by lumbar puncture. A marked behavioral syndrome characterized by confusion hypomanic/manic behavior, and psychosis followed drug administration and persisted for more than 2 days.

Original languageEnglish (US)
Pages (from-to)103-104
Number of pages2
JournalAmerican Journal of Psychiatry
Issue number1
StatePublished - 1984
Externally publishedYes


ASJC Scopus subject areas

  • Psychiatry and Mental health

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