Behavioral and psychiatric features of Sturge-Weber syndrome

Research output: Contribution to journalArticle

Abstract

Sturge-Weber syndrome (SWS) is characterized by seizures, port-wine birthmarks, vascular malformations, and rarely studied psychobehavioral features. This study describes a small group of outpatients (N = 16, age, 3-34 years) with Sturge-Weber syndrome seeking medical services (due to seizures, ophthalmological, and dermatological problems among others). The patients were screened for psychiatric diagnoses. The most frequent diagnoses were mood disorder (31%), disruptive behavior disorder (25%), and adjustment disorder (25%). A substance-related disorder was the most frequent in adults (67%). A significant association was found between disruptive behavior disorder not otherwise specified and more left frontal and left parietal involvement. A trend toward significant association of having a seizure in the past 3 months with disruptive behavior disorder not otherwise specified was observed. Problems with mood, attention, sleep, learning, and substance use were common. Disruptive behavior disorders and their association with medical conditions should be further investigated.

Original languageEnglish (US)
Pages (from-to)905-913
Number of pages9
JournalJournal of Nervous and Mental Disease
Volume198
Issue number12
DOIs
StatePublished - Dec 2010

Fingerprint

Sturge-Weber Syndrome
Attention Deficit and Disruptive Behavior Disorders
Psychiatry
Seizures
Adjustment Disorders
Vascular Malformations
Wine
Mood Disorders
Mental Disorders
Substance-Related Disorders
Sleep
Outpatients
Learning

Keywords

  • Angiomatosis
  • behavioral phenotype
  • port-wine birthmark
  • Sturge-Weber syndrome

ASJC Scopus subject areas

  • Psychiatry and Mental health

Cite this

Behavioral and psychiatric features of Sturge-Weber syndrome. / Turin, Elizabeth; Grados, Marco; Tierney, Elaine; Ferenc, Lisa M.; Zabel, Theodore A; Comi, Anne Marie Spalding.

In: Journal of Nervous and Mental Disease, Vol. 198, No. 12, 12.2010, p. 905-913.

Research output: Contribution to journalArticle

@article{8493ed457bce420485a67b32d77b535b,
title = "Behavioral and psychiatric features of Sturge-Weber syndrome",
abstract = "Sturge-Weber syndrome (SWS) is characterized by seizures, port-wine birthmarks, vascular malformations, and rarely studied psychobehavioral features. This study describes a small group of outpatients (N = 16, age, 3-34 years) with Sturge-Weber syndrome seeking medical services (due to seizures, ophthalmological, and dermatological problems among others). The patients were screened for psychiatric diagnoses. The most frequent diagnoses were mood disorder (31{\%}), disruptive behavior disorder (25{\%}), and adjustment disorder (25{\%}). A substance-related disorder was the most frequent in adults (67{\%}). A significant association was found between disruptive behavior disorder not otherwise specified and more left frontal and left parietal involvement. A trend toward significant association of having a seizure in the past 3 months with disruptive behavior disorder not otherwise specified was observed. Problems with mood, attention, sleep, learning, and substance use were common. Disruptive behavior disorders and their association with medical conditions should be further investigated.",
keywords = "Angiomatosis, behavioral phenotype, port-wine birthmark, Sturge-Weber syndrome",
author = "Elizabeth Turin and Marco Grados and Elaine Tierney and Ferenc, {Lisa M.} and Zabel, {Theodore A} and Comi, {Anne Marie Spalding}",
year = "2010",
month = "12",
doi = "10.1097/NMD.0b013e3181fe75ee",
language = "English (US)",
volume = "198",
pages = "905--913",
journal = "Journal of Nervous and Mental Disease",
issn = "0022-3018",
publisher = "Lippincott Williams and Wilkins",
number = "12",

}

TY - JOUR

T1 - Behavioral and psychiatric features of Sturge-Weber syndrome

AU - Turin, Elizabeth

AU - Grados, Marco

AU - Tierney, Elaine

AU - Ferenc, Lisa M.

AU - Zabel, Theodore A

AU - Comi, Anne Marie Spalding

PY - 2010/12

Y1 - 2010/12

N2 - Sturge-Weber syndrome (SWS) is characterized by seizures, port-wine birthmarks, vascular malformations, and rarely studied psychobehavioral features. This study describes a small group of outpatients (N = 16, age, 3-34 years) with Sturge-Weber syndrome seeking medical services (due to seizures, ophthalmological, and dermatological problems among others). The patients were screened for psychiatric diagnoses. The most frequent diagnoses were mood disorder (31%), disruptive behavior disorder (25%), and adjustment disorder (25%). A substance-related disorder was the most frequent in adults (67%). A significant association was found between disruptive behavior disorder not otherwise specified and more left frontal and left parietal involvement. A trend toward significant association of having a seizure in the past 3 months with disruptive behavior disorder not otherwise specified was observed. Problems with mood, attention, sleep, learning, and substance use were common. Disruptive behavior disorders and their association with medical conditions should be further investigated.

AB - Sturge-Weber syndrome (SWS) is characterized by seizures, port-wine birthmarks, vascular malformations, and rarely studied psychobehavioral features. This study describes a small group of outpatients (N = 16, age, 3-34 years) with Sturge-Weber syndrome seeking medical services (due to seizures, ophthalmological, and dermatological problems among others). The patients were screened for psychiatric diagnoses. The most frequent diagnoses were mood disorder (31%), disruptive behavior disorder (25%), and adjustment disorder (25%). A substance-related disorder was the most frequent in adults (67%). A significant association was found between disruptive behavior disorder not otherwise specified and more left frontal and left parietal involvement. A trend toward significant association of having a seizure in the past 3 months with disruptive behavior disorder not otherwise specified was observed. Problems with mood, attention, sleep, learning, and substance use were common. Disruptive behavior disorders and their association with medical conditions should be further investigated.

KW - Angiomatosis

KW - behavioral phenotype

KW - port-wine birthmark

KW - Sturge-Weber syndrome

UR - http://www.scopus.com/inward/record.url?scp=78650830812&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650830812&partnerID=8YFLogxK

U2 - 10.1097/NMD.0b013e3181fe75ee

DO - 10.1097/NMD.0b013e3181fe75ee

M3 - Article

C2 - 21135644

AN - SCOPUS:78650830812

VL - 198

SP - 905

EP - 913

JO - Journal of Nervous and Mental Disease

JF - Journal of Nervous and Mental Disease

SN - 0022-3018

IS - 12

ER -