Behçet's disease complicated by pylephlebitis and hepatic abscesses

A. C. Gelber, L. Schachna, L. Mitchell, G. Schwartzman, G. Hartnell, J. F. Geschwind

Research output: Contribution to journalArticle

Abstract

A 22 year old man presented with fever, abdominal pain, weight loss and diarrhea. Past medical history revealed recurrent aseptic meningitis, uveitis, and erythema nodosum. Further inquiry unveiled a prominent history of oral aphthous ulcers; all features of Behçet's disease. Imaging revealed mesenteric arteritis and pylephlebitis, septic thrombophlebitis of the portal vein, a previously unrecognized complication of Behçet's disease, with multiple intrahepatic abscesses. Portal venography demonstrated an extensively diseased, expanded, and obstructed portal venous system. Blood cultures and portal vein aspirate yielded polymicrobial flora. Percutaneous intraportal thrombolytic therapy and mechanical thrombectomy were attempted to restore flow to the portal venous system. This distinctly rare manifestation of Behçet's Disease, pylephlebitis, may result from ischemic injury and structural compromise of the bowel mucosa, resulting from underlying vasculitis.

Original languageEnglish (US)
Pages (from-to)S59-S61
JournalClinical and experimental rheumatology
Volume19
Issue number5 SUPPL. 24
StatePublished - Dec 1 2001

Keywords

  • Behçet's disease
  • Hepatic abscess
  • Pylephlebitis
  • Vasculitis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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  • Cite this

    Gelber, A. C., Schachna, L., Mitchell, L., Schwartzman, G., Hartnell, G., & Geschwind, J. F. (2001). Behçet's disease complicated by pylephlebitis and hepatic abscesses. Clinical and experimental rheumatology, 19(5 SUPPL. 24), S59-S61.