TY - JOUR
T1 - Bedside differentiation of vestibular neuritis from central "vestibular pseudoneuritis"
AU - Cnyrim, C. D.
AU - Newman-Toker, D.
AU - Karch, C.
AU - Brandt, T.
AU - Strupp, Michael
PY - 2008/4
Y1 - 2008/4
N2 - Acute unilateral peripheral and central vestibular lesions can cause similar signs and symptoms, but they require different diagnostics and management. We therefore correlated clinical signs to differentiate vestibular neuritis (40 patients) from central "vestibular pseudoneuritis" (43 patients) in the acute situation with the final diagnosis assessed by neuroimaging. Skew deviation was the only specific but non-sensitive (40%) sign for pseudoneuritis. None of the other isolated signs (head thrust test, saccadic pursuit, gaze evoked nystagmus, subjective visual vertical) were reliable; however, multivariate logistic regression increased their sensitivity and specificity to 92%.
AB - Acute unilateral peripheral and central vestibular lesions can cause similar signs and symptoms, but they require different diagnostics and management. We therefore correlated clinical signs to differentiate vestibular neuritis (40 patients) from central "vestibular pseudoneuritis" (43 patients) in the acute situation with the final diagnosis assessed by neuroimaging. Skew deviation was the only specific but non-sensitive (40%) sign for pseudoneuritis. None of the other isolated signs (head thrust test, saccadic pursuit, gaze evoked nystagmus, subjective visual vertical) were reliable; however, multivariate logistic regression increased their sensitivity and specificity to 92%.
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U2 - 10.1136/jnnp.2007.123596
DO - 10.1136/jnnp.2007.123596
M3 - Article
C2 - 18344397
AN - SCOPUS:41149098056
SN - 0022-3050
VL - 79
SP - 458
EP - 460
JO - Journal of Neurology, Neurosurgery and Psychiatry
JF - Journal of Neurology, Neurosurgery and Psychiatry
IS - 4
ER -