Abstract
BEAMing is a feasible, accurate, and sensitive method for detection of PIK3CA mutations in circulating tumor DNA in blood. Mutation status of PIK3CA may change between primary tumor and recurrence. The results suggest a new approach for noninvasive determination of current mutation status in patients with metastatic disease.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3209-3211 |
| Number of pages | 3 |
| Journal | Clinical Cancer Research |
| Volume | 18 |
| Issue number | 12 |
| DOIs |
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| State | Published - Jun 15 2012 |
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Cite this
Richardson, A. L., & Iglehart, J. D. (2012). BEAMing up personalized medicine: Mutation detection in blood. Clinical Cancer Research, 18(12), 3209-3211. https://doi.org/10.1158/1078-0432.CCR-12-0871