Bcl-2 turns deadly

Research output: Contribution to journalShort survey

Abstract

Small-molecule inhibitors of anti-apoptotic Bcl-2 proteins and BH3 mimetic peptides are promising anticancer agents. A recent study identifies a Nur77-based peptide that converts anti-apoptotic Bcl-2 proteins into proapoptotic molecules, providing another potential cancer therapeutic strategy.

Original languageEnglish (US)
Pages (from-to)722-723
Number of pages2
JournalNature chemical biology
Volume4
Issue number12
DOIs
StatePublished - Dec 2008

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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