Bcl-2 turns deadly

Bing Qi; J. Marie Hardwick

doi:10.1038/nchembio1208-722

Bcl-2 turns deadly

Bing Qi, J. Marie Hardwick

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Small-molecule inhibitors of anti-apoptotic Bcl-2 proteins and BH3 mimetic peptides are promising anticancer agents. A recent study identifies a Nur77-based peptide that converts anti-apoptotic Bcl-2 proteins into proapoptotic molecules, providing another potential cancer therapeutic strategy.

Original language	English (US)
Pages (from-to)	722-723
Number of pages	2
Journal	Nature chemical biology
Volume	4
Issue number	12
DOIs	https://doi.org/10.1038/nchembio1208-722
State	Published - Dec 2008

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1038/nchembio1208-722

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title = "Bcl-2 turns deadly",

abstract = "Small-molecule inhibitors of anti-apoptotic Bcl-2 proteins and BH3 mimetic peptides are promising anticancer agents. A recent study identifies a Nur77-based peptide that converts anti-apoptotic Bcl-2 proteins into proapoptotic molecules, providing another potential cancer therapeutic strategy.",

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Bcl-2 turns deadly

Abstract

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