Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip

Sanghoon Lee, Wendy Yen Xian Peh, John S. Ho, Nitish V Thakor, Shih Cheng Yen, Chengkuo Lee

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper demonstrates batteryless remote modulation of bladder function using an active neural clip interfaces in rats. The proposed clip interface not only provides quick and conformal implantation on a small pelvic nerve in a rat, but also applies gentle pressure on the nerve to keep the clip interface in place. This novel clip interface is integrated with a micro PCB, and components for wireless mid-field transfer. The tiny and wirelessly powered neural clip can be implanted on the small visceral pelvic nerve located deeply in the body, and it provides remote modulation of micturition in rats. This result indicates that the proposed wireless neural clip could enable wireless modulation of small peripheral somatic and visceral nerves, thus advancing implantable bioelectronics in the near future.

Original languageEnglish (US)
Title of host publicationNEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages452-455
Number of pages4
ISBN (Electronic)9781538652732
DOIs
StatePublished - Dec 3 2018
Event13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018 - Singapore, Singapore
Duration: Apr 22 2018Apr 26 2018

Other

Other13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018
CountrySingapore
CitySingapore
Period4/22/184/26/18

Keywords

  • Bioelectronic medicine
  • Bladder modulation
  • Neural clip
  • Pelvic nerve
  • Wireless

ASJC Scopus subject areas

  • Biomedical Engineering
  • Electrical and Electronic Engineering
  • Instrumentation

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