Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip

Sanghoon Lee; Wendy Yen Xian Peh; John S. Ho; Nitish V Thakor; Shih Cheng Yen; Chengkuo Lee

doi:10.1109/NEMS.2018.8556942

Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip

Sanghoon Lee, Wendy Yen Xian Peh, John S. Ho, Nitish V Thakor, Shih Cheng Yen, Chengkuo Lee

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Scopus citations

Abstract

This paper demonstrates batteryless remote modulation of bladder function using an active neural clip interfaces in rats. The proposed clip interface not only provides quick and conformal implantation on a small pelvic nerve in a rat, but also applies gentle pressure on the nerve to keep the clip interface in place. This novel clip interface is integrated with a micro PCB, and components for wireless mid-field transfer. The tiny and wirelessly powered neural clip can be implanted on the small visceral pelvic nerve located deeply in the body, and it provides remote modulation of micturition in rats. This result indicates that the proposed wireless neural clip could enable wireless modulation of small peripheral somatic and visceral nerves, thus advancing implantable bioelectronics in the near future.

Original language	English (US)
Title of host publication	NEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	452-455
Number of pages	4
ISBN (Electronic)	9781538652732
DOIs	https://doi.org/10.1109/NEMS.2018.8556942
State	Published - Dec 3 2018
Event	13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018 - Singapore, Singapore Duration: Apr 22 2018 → Apr 26 2018

Other

Other	13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018
Country/Territory	Singapore
City	Singapore
Period	4/22/18 → 4/26/18

Keywords

Bioelectronic medicine
Bladder modulation
Neural clip
Pelvic nerve
Wireless

ASJC Scopus subject areas

Biomedical Engineering
Electrical and Electronic Engineering
Instrumentation

Access to Document

10.1109/NEMS.2018.8556942

Cite this

Lee, S., Xian Peh, W. Y., Ho, J. S., Thakor, N. V., Yen, S. C., & Lee, C. (2018). Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip. In NEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems (pp. 452-455). Article 8556942 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NEMS.2018.8556942

Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip. / Lee, Sanghoon; Xian Peh, Wendy Yen; Ho, John S. et al.
NEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems. Institute of Electrical and Electronics Engineers Inc., 2018. p. 452-455 8556942.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Lee, S, Xian Peh, WY, Ho, JS, Thakor, NV, Yen, SC & Lee, C 2018, Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip. in NEMS 2018 - 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems., 8556942, Institute of Electrical and Electronics Engineers Inc., pp. 452-455, 13th Annual IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2018, Singapore, Singapore, 4/22/18. https://doi.org/10.1109/NEMS.2018.8556942

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abstract = "This paper demonstrates batteryless remote modulation of bladder function using an active neural clip interfaces in rats. The proposed clip interface not only provides quick and conformal implantation on a small pelvic nerve in a rat, but also applies gentle pressure on the nerve to keep the clip interface in place. This novel clip interface is integrated with a micro PCB, and components for wireless mid-field transfer. The tiny and wirelessly powered neural clip can be implanted on the small visceral pelvic nerve located deeply in the body, and it provides remote modulation of micturition in rats. This result indicates that the proposed wireless neural clip could enable wireless modulation of small peripheral somatic and visceral nerves, thus advancing implantable bioelectronics in the near future.",

keywords = "Bioelectronic medicine, Bladder modulation, Neural clip, Pelvic nerve, Wireless",

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Batteryless Pelvic Nerve Direct Modulation for Bladder Voding Using an Active Neural Clip

Abstract

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Keywords

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