Basic leucine zipper (bZIP) domain transcription factor MBZ1 regulates cell wall integrity, spore adherence, and virulence in Metarhizium robertsii

Wei Huang, Yanfang Shang, Peilin Chen, Kai Cen, Chengshu Wang

Research output: Contribution to journalArticle

Abstract

Background: The bZIP-type transcription factors are widely distributed in eukaryotes to control an array of biological activities. Results: MBZ1 from Metarhizium robertsii regulates fungal growth, cell wall integrity, spore adherence, and virulence against insects. Conclusion: MBZ1 is required for development and virulence of insect pathogenic fungi. Significance: The orthologs of bZIP-type transcription factors are functionally divergent in different organisms.

Original languageEnglish (US)
Pages (from-to)8218-8231
Number of pages14
JournalJournal of Biological Chemistry
Volume290
Issue number13
DOIs
StatePublished - Mar 27 2015
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

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