Barrett's esophagus: a comprehensive review and update

Syed M. Gilani, Elizabeth Montgomery

Research output: Contribution to journalReview articlepeer-review

Abstract

Barrett's esophagus (BE) is a known precursor to esophageal adenocarcinoma. In the United States, a prevalence of up to 25% is reported in high risk populations and it is identified in about 5% of patients with gastroesophageal reflux disease (GERD). The diagnosis of BE requires endoscopically identifying columnar (“salmon colored”) mucosa, taking biopsies from targeted areas and then confirming histologically. The American College of Gastroenterologists updated its criteria in 2016, introducing a length requirement. This brief review addresses diagnosis of BE and its various associated challenges; identifying dysplasia, grading it, and management.

Original languageEnglish (US)
Pages (from-to)479-486
Number of pages8
JournalDiagnostic Histopathology
Volume24
Issue number12
DOIs
StatePublished - Dec 2018

Keywords

  • Barrett's esophagus
  • dysplasia
  • gastroesophageal junction
  • management
  • z-line

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

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