Barbed Versus Standard Suture: A Randomized Trial for Laparoscopic Vaginal Cuff Closure

Jon I. Einarsson, Sarah L. Cohen, Joseph M. Gobern, Evelien M. Sandberg, Catherine I. Hill-Lydecker, Karen Wang, Douglas N. Brown

Research output: Contribution to journalArticlepeer-review

36 Scopus citations


Study Objective: To compare closure times, cuff healing, and postoperative dyspareunia between barbed and traditional sutures during laparoscopic total hysterectomy. Design: A randomized clinical trial (Canadian Task Force classification I). Setting: A university hospital. Patients: Sixty-three women undergoing total laparoscopic hysterectomy. Interventions: Total laparoscopic hysterectomy was performed using standard techniques. The vaginal cuff closure method was randomized to barbed suture (Quill; Angiotech Pharmaceuticals, Inc., Vancouver, Canada) or standard suture (Vicryl; Ethicon Inc., Somerville, NJ). The time required for cuff closure was documented. Patients were examined postoperatively to assess cuff healing, and a standardized sexual function questionnaire was administered preoperatively and at 3 months postoperatively. Measurements and Main Results: The mean vaginal cuff closure time was 10.4 minutes versus 9.6 minutes in the barbed versus standard suture group (p = .51). Cuff healing appeared similar between the 2 groups. Rates of dyspareunia, partner dyspareunia, and sexual function were similar in both groups at 3 months postoperatively. Vaginal cuff closure times were significantly faster among attendings compared with residents/fellows (7.1 vs 12.8 minutes, respectively; p < .0001). The study was designed to have a statistical power of 80% to detect a difference of 5 minutes in cuff closure time between the 2 groups (α level of 0.05). Conclusion: Laparoscopic vaginal cuff closure times are similar when using barbed sutures and braided sutures.

Original languageEnglish (US)
Pages (from-to)492-498
Number of pages7
JournalJournal of Minimally Invasive Gynecology
Issue number4
StatePublished - Jul 2013
Externally publishedYes


  • Barbed suture
  • Laparoscopy
  • Total hysterectomy
  • Vaginal cuff

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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