Banff 2003 meeting report: New diagnostic insights and standards

Lorraine C Racusen, Philip F. Halloran, Kim Solez

Research output: Contribution to journalArticle

Abstract

The Seventh Banff Conference on Allograft Pathology was held June 14-18, 2003 in Aberdeen, Scotland representing the latest iteration of the international consensus meeting, which develops world-wide standards for interpretation of allograft biopsies. The meeting is an important force behind standardized slide interpretation to strengthen endpoints in international clinical trials. Of participants polled 87% reported that they would alter clinical practice as a direct consequence of the meeting and its content. Advances were made in many areas including tubulitis mechanisms, real-time polymerase chain reaction (PCR) gene analysis and microarrays in rejection diagnosis, tolerance/accommodation/immunomodulation, he role of monocytes and macrophages in rejection and C4d as a marker for antibody-mediated rejection. A provisional scoring system for peritubular capillary inflammatory cell accumulation in antibody-mediated rejection was presented for testing, as well as plans for a nephrectomy study to determine specificity of vascular lesions of rejection. Future meetings are planned for 2005 (Edmonton), 2007 and 2009, with active ongoing Internet discussion between meetings.

Original languageEnglish (US)
Pages (from-to)1562-1566
Number of pages5
JournalAmerican Journal of Transplantation
Volume4
Issue number10
DOIs
StatePublished - Oct 2004

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Keywords

  • Banff classification
  • Central slide review
  • Scoring

ASJC Scopus subject areas

  • Immunology

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