Abstract
The Seventh Banff Conference on Allograft Pathology was held June 14-18, 2003 in Aberdeen, Scotland representing the latest iteration of the international consensus meeting, which develops world-wide standards for interpretation of allograft biopsies. The meeting is an important force behind standardized slide interpretation to strengthen endpoints in international clinical trials. Of participants polled 87% reported that they would alter clinical practice as a direct consequence of the meeting and its content. Advances were made in many areas including tubulitis mechanisms, real-time polymerase chain reaction (PCR) gene analysis and microarrays in rejection diagnosis, tolerance/accommodation/immunomodulation, he role of monocytes and macrophages in rejection and C4d as a marker for antibody-mediated rejection. A provisional scoring system for peritubular capillary inflammatory cell accumulation in antibody-mediated rejection was presented for testing, as well as plans for a nephrectomy study to determine specificity of vascular lesions of rejection. Future meetings are planned for 2005 (Edmonton), 2007 and 2009, with active ongoing Internet discussion between meetings.
Original language | English (US) |
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Pages (from-to) | 1562-1566 |
Number of pages | 5 |
Journal | American Journal of Transplantation |
Volume | 4 |
Issue number | 10 |
DOIs | |
State | Published - Oct 2004 |
Keywords
- Banff classification
- Central slide review
- Scoring
ASJC Scopus subject areas
- Immunology and Allergy
- Transplantation
- Pharmacology (medical)