Bacterial infections

Carolyn Senavsky, Noah Craft, Lloyd S. Miller

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Innate immune responses are directed against conserved components of microorganisms called pathogen-associated molecular patterns (PAMPs). The host cellular receptors that recognize different PAMPs are called pattern recognition receptors (PRRs). Two major families of human antimicrobial peptides are defensins and cathelicidin. Toll-like receptors (TLRs) are important PRRs involved in host defense against a variety of pathogenic microorganisms. Complement plays a key role in killing of bacteria. Neutrophils, monocytes, and macrophages phagocytose opsonized bacteria.

Original languageEnglish (US)
Title of host publicationClinical and Basic Immunodermatology
PublisherSpringer London
Pages335-361
Number of pages27
ISBN (Print)9781848001640
DOIs
StatePublished - Dec 1 2008
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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