B-cell activation

Stephen V. Desiderio

doi:10.1016/0952-7915(92)90073-N

B-cell activation

Stephen V. Desiderio

School of Medicine

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.

Original language	English (US)
Pages (from-to)	252-256
Number of pages	5
Journal	Current Opinion in Immunology
Volume	4
Issue number	3
DOIs	https://doi.org/10.1016/0952-7915(92)90073-N
State	Published - Jun 1992

ASJC Scopus subject areas

Immunology and Allergy
Immunology

Access to Document

10.1016/0952-7915(92)90073-N

Cite this

@article{baeda663a0e04f5bb280c5ad366d1356,

title = "B-cell activation",

abstract = "Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.",

author = "Desiderio, {Stephen V.}",

note = "Funding Information: The author thanks Susan Dymecki and Doug Fearon for comments on the manuscript. Work in the author{\textquoteright}s laboratory is supported by the Howard Hughes Medical Institute and the National Institutes of Health.",

year = "1992",

month = jun,

doi = "10.1016/0952-7915(92)90073-N",

language = "English (US)",

volume = "4",

pages = "252--256",

journal = "Current Opinion in Immunology",

issn = "0952-7915",

publisher = "Elsevier Limited",

number = "3",

}

TY - JOUR

T1 - B-cell activation

AU - Desiderio, Stephen V.

N1 - Funding Information: The author thanks Susan Dymecki and Doug Fearon for comments on the manuscript. Work in the author’s laboratory is supported by the Howard Hughes Medical Institute and the National Institutes of Health.

PY - 1992/6

Y1 - 1992/6

N2 - Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.

AB - Extraordinary progress has been made in refining our understanding of the B-cell antigen receptor complex, the role of protein-tyrosine phosphorylation as the key intermediary in immunoglobulin signal transduction, and in identifying candidate effectors of immunoglobulin-mediated signaling. In addition, the properties of a new group of G proteins may rekindle interest in older observations implicating such molecules as important in B-cell activation.

UR - http://www.scopus.com/inward/record.url?scp=0026694012&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026694012&partnerID=8YFLogxK

U2 - 10.1016/0952-7915(92)90073-N

DO - 10.1016/0952-7915(92)90073-N

M3 - Article

C2 - 1418702

AN - SCOPUS:0026694012

SN - 0952-7915

VL - 4

SP - 252

EP - 256

JO - Current Opinion in Immunology

JF - Current Opinion in Immunology

IS - 3

ER -

B-cell activation

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this