Autosomal dominant cone-rod dystrophy: A linkage study with 17 biochemical and serological markers

R. E. Ferrell, H. M. Hittner, A. Chakravarti

Research output: Contribution to journalArticle

Abstract

Five generations of a family with autosomal-dominant cone-rod dystrophy (CRD) with complete penetrance have been previously studied extensively clinically. The young members of this family were reevaluated, and blood from 73 available family members was studied with 17 biochemical and serological markers. A total of 25 relatives was found to be affected. Linkage between the gene for CRD in this family and the markers studied could not be established by maximum likelihood analysis.

Original languageEnglish (US)
Pages (from-to)363-369
Number of pages7
JournalAmerican Journal of Medical Genetics
Volume8
Issue number3
StatePublished - 1981
Externally publishedYes

Fingerprint

Biomarkers
Penetrance
Retinal Cone Dystrophy 1
Cone-Rod Dystrophies
Genes

ASJC Scopus subject areas

  • Genetics(clinical)

Cite this

Autosomal dominant cone-rod dystrophy : A linkage study with 17 biochemical and serological markers. / Ferrell, R. E.; Hittner, H. M.; Chakravarti, A.

In: American Journal of Medical Genetics, Vol. 8, No. 3, 1981, p. 363-369.

Research output: Contribution to journalArticle

Ferrell, R. E. ; Hittner, H. M. ; Chakravarti, A. / Autosomal dominant cone-rod dystrophy : A linkage study with 17 biochemical and serological markers. In: American Journal of Medical Genetics. 1981 ; Vol. 8, No. 3. pp. 363-369.
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