Autophagy and exomoses in the aged retinal pigment epithelium: Possible relevance to drusen formation and age-related macular degeneration

Agriculture & Biology

• macular degeneration 100%
• autophagy 80%
• exosomes 58%
• epithelium 54%
• pigments 51%
• DNA damage 26%
• mitochondrial DNA 22%
• mutation 18%
• chemoattractants 17%
• disease course 17%
• NADH dehydrogenase (ubiquinone) 17%
• rotenone 17%
• DNA repair 14%
• cell biology 14%
• phagocytosis 13%
• retina 13%
• pathogenesis 12%
• rodents 11%
• eyes 10%
• mice 7%
• enzymes 6%
• proteins 4%

Medicine & Life Sciences

• Retinal Pigment Epithelium 77%
• Macular Degeneration 70%
• Autophagy 64%
• Exosomes 47%
• Bruch Membrane 37%
• Mitochondrial DNA 28%
• DNA Damage 23%
• DNA Repair Enzymes 18%
• Complement Factor H 18%
• Elderly 18%
• Rotenone 17%
• Choroid 15%
• Chemotactic Factors 15%
• Mutation 15%
• Genetic Predisposition to Disease 13%
• Cell Biology 11%
• Retina 11%
• Ocular Vision 11%
• Rodentia 11%
• Tissue Donors 10%
• Eye 8%
• In Vitro Techniques 5%
• Proteins 4%

Chemical Compounds

• Retinal Pigment 91%
• Marker 59%
• Mutation 37%
• Chemoattractant 32%
• Rotenone 31%
• Phagocytic 30%
• Amorphous Material 15%
• Donor 15%
• Protein 9%