Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides

Siew Cheng Phua; Yuta Nihongaki; Takanari Inoue

doi:10.1016/j.ceb.2018.01.008

Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides

Siew Cheng Phua, Yuta Nihongaki, Takanari Inoue

School of Medicine

Research output: Contribution to journal › Review article

Abstract

The primary cilium is a cell surface projection from plasma membrane which transduces external stimuli to diverse signaling pathways. To function as an independent signaling organelle, the molecular composition of the ciliary membrane has to be distinct from that of the plasma membrane. Here, we review recent findings which have deepened our understanding of the unique yet dynamic phosphoinositide profile found in the primary cilia.

Original language	English (US)
Pages (from-to)	72-78
Number of pages	7
Journal	Current Opinion in Cell Biology
Volume	50
DOIs	https://doi.org/10.1016/j.ceb.2018.01.008
Publication status	Published - Feb 1 2018

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ASJC Scopus subject areas

Cell Biology

Cite this

Phua, S. C., Nihongaki, Y., & Inoue, T. (2018). Autonomy declared by primary cilia through compartmentalization of membrane phosphoinositides. Current Opinion in Cell Biology, 50, 72-78. https://doi.org/10.1016/j.ceb.2018.01.008

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Access to Document

10.1016/j.ceb.2018.01.008