Autonomic imaging in heart transplantation

Frank M. Bengel

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Sympathetic reinnervation of the transplanted heart is a unique example of the plasticity and regenerative capacity of the autonomic nervous system. Radionuclide imaging studies have played a key role in demonstrating that cardiac allografts regain catecholamine storage capacity, i.e., functional sympathetic nerve terminals after complete denervation due to transplant surgery. Since its initial demonstration, the regionally heterogeneous pattern of reinnervation, its time course and determinants, as well as its functional effects on the transplanted heart have been described in detail, as summarized in this chapter.

Original languageEnglish (US)
Title of host publicationAutonomic Innervation of the Heart: Role of Molecular Imaging
PublisherSpringer Berlin Heidelberg
Pages337-346
Number of pages10
ISBN (Print)9783662450741, 9783662450734
DOIs
StatePublished - Jan 1 2015
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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