TY - GEN
T1 - Automatic screening of age-related macular degeneration and retinal abnormalities
AU - Burlina, P.
AU - Freund, D. E.
AU - Dupas, B.
AU - Bressler, N.
PY - 2011
Y1 - 2011
N2 - We describe a novel approach for screening retinal imagery to detect evidence of abnormalities. In this paper, we focus our efforts on age-related macular degeneration (AMD), a pathology that may often go undetected in the early or intermediate stages, and can lead to a neovascular form often resulting in blindness, if untreated. Our strategy for retinal anomaly detection is to employ a single class classifier applied to fundus imagery. We use a multiresolution locally-adaptive scheme that identifies both normal and anomalous regions within the retina. We do this by using a hybrid parametric/non-parametric characterization of the support of the probability distribution of normal retinal tissue in color and intensity feature space. We apply this approach to screen for evidence of AMD on a dataset of 66 healthy and pathological cases and found a detection sensitivity and specificity of 95% and 96%.
AB - We describe a novel approach for screening retinal imagery to detect evidence of abnormalities. In this paper, we focus our efforts on age-related macular degeneration (AMD), a pathology that may often go undetected in the early or intermediate stages, and can lead to a neovascular form often resulting in blindness, if untreated. Our strategy for retinal anomaly detection is to employ a single class classifier applied to fundus imagery. We use a multiresolution locally-adaptive scheme that identifies both normal and anomalous regions within the retina. We do this by using a hybrid parametric/non-parametric characterization of the support of the probability distribution of normal retinal tissue in color and intensity feature space. We apply this approach to screen for evidence of AMD on a dataset of 66 healthy and pathological cases and found a detection sensitivity and specificity of 95% and 96%.
UR - http://www.scopus.com/inward/record.url?scp=84055212013&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84055212013&partnerID=8YFLogxK
U2 - 10.1109/IEMBS.2011.6090984
DO - 10.1109/IEMBS.2011.6090984
M3 - Conference contribution
C2 - 22255207
AN - SCOPUS:84055212013
SN - 9781424441211
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 3962
EP - 3966
BT - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
T2 - 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Y2 - 30 August 2011 through 3 September 2011
ER -