TY - JOUR
T1 - Automatic bone removal for 3D TACE planning with C-arm CBCT
T2 - Evaluation of technical feasibility
AU - Wang, Zhijun
AU - Hansis, Eberhard
AU - Chen, Rongxin
AU - Duran, Rafael
AU - Chapiro, Julius
AU - Sheu, Yun Robert
AU - Kobeiter, Hicham
AU - Grass, Michael
AU - Geschwind, Jean François
AU - Lin, Mingde
N1 - Funding Information:
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper. Support for this work was provided by NIH/NCI R01 CA160771, P30 CA006973, Philips Research North America, Cambridge, MA, USA, the Rolf W. Guenther Foundation for Radiological Science, and the Beijing Nova Program (Z121107002512127)
Publisher Copyright:
© 2016 Taylor & Francis.
PY - 2016/5/3
Y1 - 2016/5/3
N2 - Purpose To evaluate the technical feasibility of automatically removing the ribs and spine from C-arm cone-beam computed tomography (CBCT) images acquired during transcatheter arterial chemoembolization (TACE). Material and methods Fifty-eight patients (45.8 ± 5.0 years) with unresectable hepatocellular carcinoma (HCC) underwent transcatheter arterial chemoembolization and had intraprocedural CBCT imaging. Automatic bone removal was performed using model-based segmentation of the ventral cavity. Two interventional radiologists independently evaluated the performance of bone removal, remaining soft tissue retention, and general usability (where both the bone is appropriately removed while retaining soft tissue) for 3D TACE planning on a four-level (complete/excellent, adequate/good, incomplete/questionable, insufficient/bad) score. The proportion of inter-reader agreement was calculated. Results For ribs and spine removal, 98.3-100% and 100% of cases showed complete or adequate performance, respectively. In 96.6% of the cases, soft tissue was at least adequately retained. 91.3-93.1% of the cases demonstrated good or excellent general usability for TACE planning. Satisfactory inter-reader agreement proportion was achieved in ribs (93.1%) and spine removal (89.7%), soft tissue retention (84.5%), and general usability for TACE planning (72.4%). Conclusion Intraprocedural automatic bone removal on CBCT images is technically feasible and offers good removal of ribs and spine while preserving soft tissue. Its clinical value needs further assessment.
AB - Purpose To evaluate the technical feasibility of automatically removing the ribs and spine from C-arm cone-beam computed tomography (CBCT) images acquired during transcatheter arterial chemoembolization (TACE). Material and methods Fifty-eight patients (45.8 ± 5.0 years) with unresectable hepatocellular carcinoma (HCC) underwent transcatheter arterial chemoembolization and had intraprocedural CBCT imaging. Automatic bone removal was performed using model-based segmentation of the ventral cavity. Two interventional radiologists independently evaluated the performance of bone removal, remaining soft tissue retention, and general usability (where both the bone is appropriately removed while retaining soft tissue) for 3D TACE planning on a four-level (complete/excellent, adequate/good, incomplete/questionable, insufficient/bad) score. The proportion of inter-reader agreement was calculated. Results For ribs and spine removal, 98.3-100% and 100% of cases showed complete or adequate performance, respectively. In 96.6% of the cases, soft tissue was at least adequately retained. 91.3-93.1% of the cases demonstrated good or excellent general usability for TACE planning. Satisfactory inter-reader agreement proportion was achieved in ribs (93.1%) and spine removal (89.7%), soft tissue retention (84.5%), and general usability for TACE planning (72.4%). Conclusion Intraprocedural automatic bone removal on CBCT images is technically feasible and offers good removal of ribs and spine while preserving soft tissue. Its clinical value needs further assessment.
KW - Hepatocellular carcinoma
KW - automatic bone removal
KW - cone-beam computed tomography
KW - three-dimensional
KW - transcatheter arterial chemoembolization
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U2 - 10.3109/13645706.2015.1129970
DO - 10.3109/13645706.2015.1129970
M3 - Article
C2 - 26923140
AN - SCOPUS:84961200587
VL - 25
SP - 162
EP - 170
JO - Minimally Invasive Therapy and Allied Technologies
JF - Minimally Invasive Therapy and Allied Technologies
SN - 1364-5706
IS - 3
ER -