Automated reconstruction of the cerebral cortex in multiple sclerosis patients

N. Shiee, P. L. Bazin, Daniel S. Reich, D. L. Pham

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Although cortical atrophy in multiple sclerosis (MS) has been reported in the literature, most cortical reconstruction techniques do not account for lesions. In this work, we propose an automated pipeline for cortical reconstruction from magnetic resonance brain images with MS lesions. The pipeline extends previously well validated methods to allow for the presence of lesions and to accommodate multichannel imaging. We validate this approach on simulated and real images. Application of the pipeline to 103 MS brains produces thickness measurements that agree well with the literature.

Original languageEnglish (US)
Title of host publicationProceedings - 2009 IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2009
Pages1334-1337
Number of pages4
DOIs
StatePublished - Nov 17 2009
Event2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009 - Boston, MA, United States
Duration: Jun 28 2009Jul 1 2009

Publication series

NameProceedings - 2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009

Other

Other2009 IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2009
Country/TerritoryUnited States
CityBoston, MA
Period6/28/097/1/09

Keywords

  • Cortical reconstruction
  • Cortical thickness
  • Lesion segmentation
  • Multiple sclerosis

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Fingerprint

Dive into the research topics of 'Automated reconstruction of the cerebral cortex in multiple sclerosis patients'. Together they form a unique fingerprint.

Cite this