Autoimmune Myopathies

Andrew L. Mammen

doi:10.1212/01.CON.0000511070.50715.ab

Autoimmune Myopathies

Andrew L. Mammen

Research output: Contribution to journal › Review article › peer-review

Abstract

Purpose of Review: This article provides guidelines for diagnosing and treating the different subtypes of autoimmune myopathies. Recent Findings: The most common subtypes of autoimmune myopathies are dermatomyositis, immune-mediated necrotizing myopathy, antisynthetase syndrome, and overlap syndromes; isolated polymyositis is an exceptionally rare disease. Specific autoantibodies are associated with unique clinical phenotypes and may be used for diagnostic and prognostic purposes, such as to assess the risk of coexisting malignancy. Summary: Diagnosing the specific subtype of autoimmune myopathy can be achieved by combining relevant features of the history, neuromuscular examination, muscle biopsy, and serologic studies.

Original language	English (US)
Pages (from-to)	1852-1870
Number of pages	19
Journal	CONTINUUM Lifelong Learning in Neurology
Volume	22
Issue number	6
DOIs	https://doi.org/10.1212/01.CON.0000511070.50715.ab
State	Published - Dec 1 2016
Externally published	Yes

ASJC Scopus subject areas

Clinical Neurology
Genetics(clinical)

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abstract = "Purpose of Review: This article provides guidelines for diagnosing and treating the different subtypes of autoimmune myopathies. Recent Findings: The most common subtypes of autoimmune myopathies are dermatomyositis, immune-mediated necrotizing myopathy, antisynthetase syndrome, and overlap syndromes; isolated polymyositis is an exceptionally rare disease. Specific autoantibodies are associated with unique clinical phenotypes and may be used for diagnostic and prognostic purposes, such as to assess the risk of coexisting malignancy. Summary: Diagnosing the specific subtype of autoimmune myopathy can be achieved by combining relevant features of the history, neuromuscular examination, muscle biopsy, and serologic studies.",

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N2 - Purpose of Review: This article provides guidelines for diagnosing and treating the different subtypes of autoimmune myopathies. Recent Findings: The most common subtypes of autoimmune myopathies are dermatomyositis, immune-mediated necrotizing myopathy, antisynthetase syndrome, and overlap syndromes; isolated polymyositis is an exceptionally rare disease. Specific autoantibodies are associated with unique clinical phenotypes and may be used for diagnostic and prognostic purposes, such as to assess the risk of coexisting malignancy. Summary: Diagnosing the specific subtype of autoimmune myopathy can be achieved by combining relevant features of the history, neuromuscular examination, muscle biopsy, and serologic studies.

AB - Purpose of Review: This article provides guidelines for diagnosing and treating the different subtypes of autoimmune myopathies. Recent Findings: The most common subtypes of autoimmune myopathies are dermatomyositis, immune-mediated necrotizing myopathy, antisynthetase syndrome, and overlap syndromes; isolated polymyositis is an exceptionally rare disease. Specific autoantibodies are associated with unique clinical phenotypes and may be used for diagnostic and prognostic purposes, such as to assess the risk of coexisting malignancy. Summary: Diagnosing the specific subtype of autoimmune myopathy can be achieved by combining relevant features of the history, neuromuscular examination, muscle biopsy, and serologic studies.

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Autoimmune Myopathies

Abstract

ASJC Scopus subject areas

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