Abstract
Early granulocytic and later mononuclear infiltration of the thyroid was produced in mice by injection of mouse antisera to mouse thyroid extract. The lesions were first seen 4 days after injection and persisted as long as 40 days. Similar effects resulted from injection of antigen-antibody mixtures produced in antigen excess. The biphasic cellular response to immune serum suggests a two-phase mechanism in the induction of passive autoimmune thyroiditis in the mouse.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 511-518 |
| Number of pages | 8 |
| Journal | Clinical Immunology and Immunopathology |
| Volume | 4 |
| Issue number | 4 |
| DOIs | |
| State | Published - Nov 1975 |
ASJC Scopus subject areas
- Immunology and Allergy
- Pathology and Forensic Medicine
- Immunology
Fingerprint Dive into the research topics of 'Autoimmune murine thyroiditis VII: Induction of the thyroid lesions by passive transfer of immune serum'. Together they form a unique fingerprint.
Cite this
Tomazic, V., & Rose, N. R. (1975). Autoimmune murine thyroiditis VII: Induction of the thyroid lesions by passive transfer of immune serum. Clinical Immunology and Immunopathology, 4(4), 511-518. https://doi.org/10.1016/0090-1229(75)90092-6