TY - JOUR
T1 - Autoimmune hepatitis
AU - Li, Ding You
AU - Schwarz, Kathleen B.
PY - 2004/2
Y1 - 2004/2
N2 - Autoimmune hepatitis affects all ages with a peak incidence in preadolescent girls. The pathogenesis of autoimmune hepatitis has not been defined. Susceptibility, clinical manifestations, and treatment outcomes are affected by environmental factors, individual immunoregulatory responses, genetic factors, age and gender. An international panel has developed diagnostic criteria for autoimmune hepatitis, and a scoring system to assess the strength of the diagnosis has also been proposed. This article discusses the diagnosis and treatment of the three types of autoimmune hepatitis proposed based on characteristic autoantibody profiles, as well as de novo autoimmune hepatitis, a new type of autoimmune hepatitis that has been recently described in liver transplant recipients without previous autoimmune disease.
AB - Autoimmune hepatitis affects all ages with a peak incidence in preadolescent girls. The pathogenesis of autoimmune hepatitis has not been defined. Susceptibility, clinical manifestations, and treatment outcomes are affected by environmental factors, individual immunoregulatory responses, genetic factors, age and gender. An international panel has developed diagnostic criteria for autoimmune hepatitis, and a scoring system to assess the strength of the diagnosis has also been proposed. This article discusses the diagnosis and treatment of the three types of autoimmune hepatitis proposed based on characteristic autoantibody profiles, as well as de novo autoimmune hepatitis, a new type of autoimmune hepatitis that has been recently described in liver transplant recipients without previous autoimmune disease.
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U2 - 10.1016/j.admecli.2003.11.009
DO - 10.1016/j.admecli.2003.11.009
M3 - Review article
C2 - 15272261
AN - SCOPUS:3142750511
SN - 1547-3368
VL - 15
SP - 131
EP - 143
JO - Adolescent Medicine Clinics
JF - Adolescent Medicine Clinics
IS - 1
ER -