TY - JOUR
T1 - Autoimmune Hemolytic Anemia with Reticulocytopenia and Erythroid Marrow
AU - Conley, C. Lockard
AU - Lippman, Scott M.
AU - Ness, Paul M.
AU - Petz, Lawrence D.
AU - Branch, Donald R.
AU - Gallagher, Michael T.
PY - 1982/2/4
Y1 - 1982/2/4
N2 - IN the course of a hemolytic disorder, episodes may occur during which reticulocytes virtually disappear from the blood, with the result that uncompensated destruction of red cells leads to progressively severe anemia.“Aplastic crises” were first described in hereditary spherocytosis1 and have been observed in many other hemolytic states, including autoimmune hemolytic anemia (AIHA).2 3 4 5 6 7 Often attributable to intercurrent infection, the episodes are usually brief and characterized by transient absence of red-cell precursors from the marrow. In some cases of AIHA, there are prolonged periods of reticulocytopenia, at times accompanied by leukopenia, thrombocytopenia, and hypoplastic marrow.8 9 10 In other cases, severe reticulocytopenia. . .
AB - IN the course of a hemolytic disorder, episodes may occur during which reticulocytes virtually disappear from the blood, with the result that uncompensated destruction of red cells leads to progressively severe anemia.“Aplastic crises” were first described in hereditary spherocytosis1 and have been observed in many other hemolytic states, including autoimmune hemolytic anemia (AIHA).2 3 4 5 6 7 Often attributable to intercurrent infection, the episodes are usually brief and characterized by transient absence of red-cell precursors from the marrow. In some cases of AIHA, there are prolonged periods of reticulocytopenia, at times accompanied by leukopenia, thrombocytopenia, and hypoplastic marrow.8 9 10 In other cases, severe reticulocytopenia. . .
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U2 - 10.1056/NEJM198202043060507
DO - 10.1056/NEJM198202043060507
M3 - Article
C2 - 7054700
AN - SCOPUS:0020074626
VL - 306
SP - 281
EP - 286
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 5
ER -