Abstract
Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 292-295 |
| Number of pages | 4 |
| Journal | Annals of Diagnostic Pathology |
| Volume | 14 |
| Issue number | 4 |
| DOIs | |
| State | Published - Aug 2010 |
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Keywords
- Auer rod-like inclusions
- B-cell leukemia
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Auer rod-like inclusions in a low-grade B-cell leukemia. / Hristov, Alexandra C.; Saladino, Andrew; Nava, Victor E.; Gocke, Christopher.
In: Annals of Diagnostic Pathology, Vol. 14, No. 4, 08.2010, p. 292-295.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Auer rod-like inclusions in a low-grade B-cell leukemia
AU - Hristov, Alexandra C.
AU - Saladino, Andrew
AU - Nava, Victor E.
AU - Gocke, Christopher
PY - 2010/8
Y1 - 2010/8
N2 - Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.
AB - Auer rods define neoplastic blasts of myeloid origin. However, azurophilic, needle-shaped, Auer rod-like inclusions have rarely been reported in the neoplastic cells of patients with B-cell malignancies, including chronic lymphocytic leukemia/small lymphocytic lymphoma. Here, we report a case of low-grade B-cell leukemia most consistent with chronic lymphocytic leukemia/small lymphocytic lymphoma that displayed numerous intracytoplasmic, needle-shaped, azurophilic rods resembling Auer rods. Furthermore, we review the literature on Auer rod-like structures in B-cell neoplasms.
KW - Auer rod-like inclusions
KW - B-cell leukemia
UR - http://www.scopus.com/inward/record.url?scp=77955665119&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77955665119&partnerID=8YFLogxK
U2 - 10.1016/j.anndiagpath.2009.07.005
DO - 10.1016/j.anndiagpath.2009.07.005
M3 - Article
C2 - 20637437
AN - SCOPUS:77955665119
VL - 14
SP - 292
EP - 295
JO - Annals of Diagnostic Pathology
JF - Annals of Diagnostic Pathology
SN - 1092-9134
IS - 4
ER -