Abstract
We studied three patients with metachromatic leukodystrophy, two with late infantile onset and one with juvenile onset. Auditory brainstem responses were abnormal in all patients, including a 14-month-old child who was asymptomatic, with normal neurologic examination and peripheral nerve conduction studies. Auditory brainstem responses therefore indicated early pathology. A new high-performance liquid chromatography assay was used to quantitate the urinary sulfatide excretion at the picomole level.
Original language | English (US) |
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Pages (from-to) | 980-985 |
Number of pages | 6 |
Journal | Neurology |
Volume | 31 |
Issue number | 8 |
DOIs | |
State | Published - Aug 1981 |
ASJC Scopus subject areas
- Clinical Neurology