Attempted prevention of diarrheal disease in Apache children with a non absorbable broad spectrum antimicrobial

N. Hirschhorn; W. E. Woodward; L. K. Evans; G. H. Chickadonz; R. S. Gordon; R. B. Sack; M. Breutzman; R. A. Cash; P. D. Zieve

doi:10.4269/ajtmh.1975.24.320

Attempted prevention of diarrheal disease in Apache children with a non absorbable broad spectrum antimicrobial

N. Hirschhorn, W. E. Woodward, L. K. Evans, G. H. Chickadonz, R. S. Gordon, R. B. Sack, M. Breutzman, R. A. Cash, P. D. Zieve

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A double blind study was conducted to test the prophylactic effect of a nonabsorbable broad spectrum antimicrobial (oral colistin sulfate) against acute diarrhea in Apache children. Children 1 to 6 mth old had over twice the morbidity from diarrhea if assigned to the antimicrobial group as compared to placebo, while the toddler group (7 to 30 mth) taking the antimicrobial had somewhat less diarrhea. Enteropathogenic E. coli was significantly more often isolated from the antimicrobial group (but only in well children). No special effect on the children's growth by the antimicrobial was discerned.

Original language	English (US)
Pages (from-to)	320-325
Number of pages	6
Journal	Unknown Journal
Volume	24
Issue number	2
DOIs	https://doi.org/10.4269/ajtmh.1975.24.320
State	Published - 1975
Externally published	Yes

ASJC Scopus subject areas

Parasitology
Virology
Infectious Diseases

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10.4269/ajtmh.1975.24.320

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title = "Attempted prevention of diarrheal disease in Apache children with a non absorbable broad spectrum antimicrobial",

abstract = "A double blind study was conducted to test the prophylactic effect of a nonabsorbable broad spectrum antimicrobial (oral colistin sulfate) against acute diarrhea in Apache children. Children 1 to 6 mth old had over twice the morbidity from diarrhea if assigned to the antimicrobial group as compared to placebo, while the toddler group (7 to 30 mth) taking the antimicrobial had somewhat less diarrhea. Enteropathogenic E. coli was significantly more often isolated from the antimicrobial group (but only in well children). No special effect on the children's growth by the antimicrobial was discerned.",

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doi = "10.4269/ajtmh.1975.24.320",

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T1 - Attempted prevention of diarrheal disease in Apache children with a non absorbable broad spectrum antimicrobial

AU - Hirschhorn, N.

AU - Woodward, W. E.

AU - Evans, L. K.

AU - Chickadonz, G. H.

AU - Gordon, R. S.

AU - Sack, R. B.

AU - Breutzman, M.

AU - Cash, R. A.

AU - Zieve, P. D.

PY - 1975

Y1 - 1975

N2 - A double blind study was conducted to test the prophylactic effect of a nonabsorbable broad spectrum antimicrobial (oral colistin sulfate) against acute diarrhea in Apache children. Children 1 to 6 mth old had over twice the morbidity from diarrhea if assigned to the antimicrobial group as compared to placebo, while the toddler group (7 to 30 mth) taking the antimicrobial had somewhat less diarrhea. Enteropathogenic E. coli was significantly more often isolated from the antimicrobial group (but only in well children). No special effect on the children's growth by the antimicrobial was discerned.

AB - A double blind study was conducted to test the prophylactic effect of a nonabsorbable broad spectrum antimicrobial (oral colistin sulfate) against acute diarrhea in Apache children. Children 1 to 6 mth old had over twice the morbidity from diarrhea if assigned to the antimicrobial group as compared to placebo, while the toddler group (7 to 30 mth) taking the antimicrobial had somewhat less diarrhea. Enteropathogenic E. coli was significantly more often isolated from the antimicrobial group (but only in well children). No special effect on the children's growth by the antimicrobial was discerned.

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Attempted prevention of diarrheal disease in Apache children with a non absorbable broad spectrum antimicrobial

Abstract

ASJC Scopus subject areas

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