Abstract
A new approach to creating an interatrial communication using a stationary fixeddiameter angioplasty balloon is presented. Stationary balloon septostomy was used to create an atrial communication in 19 young swine using a transseptal technique through a closed atrial septum, and in 18 newborn lambs through a patent foramen ovale. In animals with an intact septum, there was persistent patency of the atrial communication using balloons larger than 12 mm in diameter. The average diameter of the atrial communication was 96% of the expanded diameter of the angioplasty balloon. For newborn lambs with a patent foramen, a smooth oval atrial communication was noted by 4 weeks, and there was persistent patency of the opening using balloons larger than 15 mm in diameter. The average diameter of the opening was 81% of the diameter of the angioplasty balloon used. The new procedure was used successfully in five patients. All five showed resolution of the clinical symptomology. In conclusion, stationary angioplasty balloon atrial septostomy has been effective in producing interatrial communications, which remained patent for 4-14 weeks, in animals with intact septum, as well as in those with a patent foramen ovale.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1-7 |
| Number of pages | 7 |
| Journal | Pediatric Cardiology |
| Volume | 15 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1994 |
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Keywords
- Atrial septal defect
- Balloon atrial septostomy
- Blade atrial septostomy
- Cyanotic congenital heart disease
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Cardiology and Cardiovascular Medicine
Cite this
Atrial septostomy : Stationary angioplasty balloon technique-experimental work and preliminary clinical applications. / Mitchell, Sally E; Anderson, J. H.; Swindle, M. M.; Strandberg, J. D.; Kan, J.
In: Pediatric Cardiology, Vol. 15, No. 1, 01.1994, p. 1-7.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Atrial septostomy
T2 - Stationary angioplasty balloon technique-experimental work and preliminary clinical applications
AU - Mitchell, Sally E
AU - Anderson, J. H.
AU - Swindle, M. M.
AU - Strandberg, J. D.
AU - Kan, J.
PY - 1994/1
Y1 - 1994/1
N2 - A new approach to creating an interatrial communication using a stationary fixeddiameter angioplasty balloon is presented. Stationary balloon septostomy was used to create an atrial communication in 19 young swine using a transseptal technique through a closed atrial septum, and in 18 newborn lambs through a patent foramen ovale. In animals with an intact septum, there was persistent patency of the atrial communication using balloons larger than 12 mm in diameter. The average diameter of the atrial communication was 96% of the expanded diameter of the angioplasty balloon. For newborn lambs with a patent foramen, a smooth oval atrial communication was noted by 4 weeks, and there was persistent patency of the opening using balloons larger than 15 mm in diameter. The average diameter of the opening was 81% of the diameter of the angioplasty balloon used. The new procedure was used successfully in five patients. All five showed resolution of the clinical symptomology. In conclusion, stationary angioplasty balloon atrial septostomy has been effective in producing interatrial communications, which remained patent for 4-14 weeks, in animals with intact septum, as well as in those with a patent foramen ovale.
AB - A new approach to creating an interatrial communication using a stationary fixeddiameter angioplasty balloon is presented. Stationary balloon septostomy was used to create an atrial communication in 19 young swine using a transseptal technique through a closed atrial septum, and in 18 newborn lambs through a patent foramen ovale. In animals with an intact septum, there was persistent patency of the atrial communication using balloons larger than 12 mm in diameter. The average diameter of the atrial communication was 96% of the expanded diameter of the angioplasty balloon. For newborn lambs with a patent foramen, a smooth oval atrial communication was noted by 4 weeks, and there was persistent patency of the opening using balloons larger than 15 mm in diameter. The average diameter of the opening was 81% of the diameter of the angioplasty balloon used. The new procedure was used successfully in five patients. All five showed resolution of the clinical symptomology. In conclusion, stationary angioplasty balloon atrial septostomy has been effective in producing interatrial communications, which remained patent for 4-14 weeks, in animals with intact septum, as well as in those with a patent foramen ovale.
KW - Atrial septal defect
KW - Balloon atrial septostomy
KW - Blade atrial septostomy
KW - Cyanotic congenital heart disease
UR - http://www.scopus.com/inward/record.url?scp=0028081902&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028081902&partnerID=8YFLogxK
U2 - 10.1007/BF00796998
DO - 10.1007/BF00796998
M3 - Article
C2 - 8115265
AN - SCOPUS:0028081902
VL - 15
SP - 1
EP - 7
JO - Pediatric Cardiology
JF - Pediatric Cardiology
SN - 0172-0643
IS - 1
ER -