TY - JOUR
T1 - Atherosclerosis monitoring in the elderly using magnetic resonance imaging
T2 - Is the extra step needed?
AU - Gottlieb, Ilan
AU - Xavier, Sérgio Salles
AU - Lima, João A.C.
N1 - Copyright:
Copyright 2010 Elsevier B.V., All rights reserved.
PY - 2007/11
Y1 - 2007/11
N2 - Atherosclerotic disease represents an enormous burden in the elderly population, yet elderly patients are underrepresented in clinical trials and receive lower standard-of-care treatment compared with similar-risk younger individuals. Magnetic resonance imaging (MRI) is a powerful noninvasive imaging technique that can target atherosclerotic lesions and help better understand the pathophysiologic process of this disease in the elderly. Cholesterol-targeted interventions have improved the outcomes in patients with atherosclerotic disease, but clearly additional efforts are needed. Whether medical therapy can be effectively adjusted based on atherosclerosis progression revealed by MRI is still to be proven, but the technique certainly looks promising.
AB - Atherosclerotic disease represents an enormous burden in the elderly population, yet elderly patients are underrepresented in clinical trials and receive lower standard-of-care treatment compared with similar-risk younger individuals. Magnetic resonance imaging (MRI) is a powerful noninvasive imaging technique that can target atherosclerotic lesions and help better understand the pathophysiologic process of this disease in the elderly. Cholesterol-targeted interventions have improved the outcomes in patients with atherosclerotic disease, but clearly additional efforts are needed. Whether medical therapy can be effectively adjusted based on atherosclerosis progression revealed by MRI is still to be proven, but the technique certainly looks promising.
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U2 - 10.1111/j.1076-7460.2007.07638.x
DO - 10.1111/j.1076-7460.2007.07638.x
M3 - Review article
C2 - 17975336
AN - SCOPUS:39049104051
SN - 1076-7460
VL - 16
SP - 363
EP - 368
JO - American Journal of Geriatric Cardiology
JF - American Journal of Geriatric Cardiology
IS - 6
ER -