Asystole in ultrabrief pulse electroconvulsive therapy

Jennifer Marie Coughlin, Kyle Rodenbach, Pin Hsuan Lee, Mathew J. Hayat, Margaret M. Griffin, Marek A Mirski, Irving M Reti

Research output: Contribution to journalArticle

Abstract

Objectives: Ultrabrief (UB) pulse electroconvulsive therapy (ECT) has been gaining popularity in recent years because of its improved cognitive adverse effect profile compared with treatments triggered by brief pulses. When delivered at maximal charge, UB pulses are administered for 8 seconds. Because electrical stimulation triggers a parasympathetic surge and transient asystole, we checked whether UB pulses delivered for 8 seconds were associated with prolonged cardiac pause compared with maximal charge delivered for 4 seconds with brief pulses. Methods: This is a retrospective study of cardiac pause length of all patients undergoing ECT treatment at The Johns Hopkins Hospital during 1 year. Results: Electrocardiac pause length for patients undergoing ECT with right unilateral placement at maximal charge was not affected by pulse width. However, we did find cardiac pause length to be sensitive to 2- versus 4-second duration stimuli using brief pulses (P <0.0001). Conclusions: Notwithstanding the clear limitations of small sample size and retrospective design, we found that right unilateral ECT was not affected by pulse width when maximal charge was delivered.

Original languageEnglish (US)
Pages (from-to)165-169
Number of pages5
JournalJournal of ECT
Volume28
Issue number3
DOIs
StatePublished - Sep 2012

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Electroconvulsive Therapy
Heart Arrest
Sample Size
Electric Stimulation
Retrospective Studies
Therapeutics

Keywords

  • asystole
  • bradycardia
  • electroconvulsive therapy
  • pulse width
  • ultrabrief

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Neuroscience (miscellaneous)

Cite this

Asystole in ultrabrief pulse electroconvulsive therapy. / Coughlin, Jennifer Marie; Rodenbach, Kyle; Lee, Pin Hsuan; Hayat, Mathew J.; Griffin, Margaret M.; Mirski, Marek A; Reti, Irving M.

In: Journal of ECT, Vol. 28, No. 3, 09.2012, p. 165-169.

Research output: Contribution to journalArticle

Coughlin, Jennifer Marie ; Rodenbach, Kyle ; Lee, Pin Hsuan ; Hayat, Mathew J. ; Griffin, Margaret M. ; Mirski, Marek A ; Reti, Irving M. / Asystole in ultrabrief pulse electroconvulsive therapy. In: Journal of ECT. 2012 ; Vol. 28, No. 3. pp. 165-169.
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