Asymmetrical cerebrovascular response to right and left hemisphere cortical suction lesions in the rat

Russell L. Margolis, Ronald S. Black, Robert G. Robinson

Research output: Contribution to journalArticlepeer-review

Abstract

We have previously demonstrated that focal lesions of the right but not left cerebral cortex in the rat produce hyperactivity and depletions of norepinephrine. To assess the cerebrovascular response to suction lesions, postoperative rats were infused intravenously with [14C]inulin. The brain inulin concentration in the right lesion group was significantly higher than control (no surgery) or left lesion groups in all cortical quadrants, but most prominently in the quadrant posterior and contralateral to the lesion site.

Original languageEnglish (US)
Pages (from-to)337-340
Number of pages4
JournalBrain research
Volume308
Issue number2
DOIs
StatePublished - Aug 13 1984

Keywords

  • asymmetry
  • cerebral cortex
  • cortical lesion
  • rat cerebral vasculature

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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