TY - JOUR
T1 - Associations of accelerometer-based sleep duration and self-reported sleep difficulties with cognitive function in late mid-life
T2 - the Finnish Retirement and Aging Study
AU - Teräs, Tea
AU - Rovio, Suvi
AU - Spira, Adam P.
AU - Myllyntausta, Saana
AU - Pulakka, Anna
AU - Vahtera, Jussi
AU - Stenholm, Sari
N1 - Funding Information:
This work was supported by the Academy of Finland (Grants 286294 , 294154 and 319246 to SS); Hospital District of South-West Finland (SS), Juho Vainio Foundation (SR and SM), Yrjö Jahnsson Foundation (SR), Finnish Cultural Foundation (SR), Finnish Cultural Foundation Varsinais-Suomi Regional Found (SR) and Finnish Foundation for Cardiovascular Research (SR), Päivikki and Sakari Sohlberg Foundation (AP). The authors want to thank the FIREA participants for their willingness to participate in the study and the FIREA study staff members for their contribution in the data collection. In addition, the authors wish to acknowledge CSC – IT Center for Science, Finland, for computational resources and support.
Funding Information:
This work was supported by the Academy of Finland (Grants 286294, 294154 and 319246 to SS); Hospital District of South-West Finland (SS), Juho Vainio Foundation (SR and SM), Yrj? Jahnsson Foundation (SR), Finnish Cultural Foundation (SR), Finnish Cultural Foundation Varsinais-Suomi Regional Found (SR) and Finnish Foundation for Cardiovascular Research (SR), P?ivikki and Sakari Sohlberg Foundation (AP). The authors want to thank the FIREA participants for their willingness to participate in the study and the FIREA study staff members for their contribution in the data collection. In addition, the authors wish to acknowledge CSC ? IT Center for Science, Finland, for computational resources and support.
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2020/4
Y1 - 2020/4
N2 - Objectives: Prior evidence suggests that sleep duration and sleep difficulties may be associated with cognitive function in old age, but little is known about the sleep–cognition association in late mid-life. Our aim was to examine the associations of accelerometer-based sleep duration as well as subjective sleep difficulties with different domains of cognitive function among aging workers. Methods: The study population consisted of 289 participants (mean age 62.4 years, SD 1.02; 83% women) from the Finnish Retirement and Aging Study (FIREA). Sleep difficulties were measured using Jenkins Sleep Problem Scale (difficulties falling asleep, difficulties maintaining sleep, waking up too early in the morning, and nonrestorative sleep). Sleep duration was measured with wrist-worn accelerometer and self-report, and participants were divided into short (<7 h/night), mid-range (7–9 h/night) and long (≥9 h/night) sleepers. Participants underwent extensive cognitive testing covering three domains: (1) memory, (2) executive function, and (3) attention and information processing. Results: Greater difficulties in waking up too early in the morning were associated with poorer executive function measured with Spatial Working Memory (SWM) test (p = 0.005). Additionally, nonrestorative sleep was associated with poorer executive function measured with Trail Making Test, B–A, (p = 0.036) and borderline significantly with lower SWM (p = 0.056). Compared to mid-range sleepers, long sleepers tended to have poorer cognitive function (all memory function tests and SWM), but the associations were not statistically significant due to small number of long sleepers. Conclusions: Subjective sleep difficulties may be linked to poorer executive function in a relatively healthy population of older workers in their 60 s. Thus, promoting good sleep quality may translate into better cognitive health in late mid-life.
AB - Objectives: Prior evidence suggests that sleep duration and sleep difficulties may be associated with cognitive function in old age, but little is known about the sleep–cognition association in late mid-life. Our aim was to examine the associations of accelerometer-based sleep duration as well as subjective sleep difficulties with different domains of cognitive function among aging workers. Methods: The study population consisted of 289 participants (mean age 62.4 years, SD 1.02; 83% women) from the Finnish Retirement and Aging Study (FIREA). Sleep difficulties were measured using Jenkins Sleep Problem Scale (difficulties falling asleep, difficulties maintaining sleep, waking up too early in the morning, and nonrestorative sleep). Sleep duration was measured with wrist-worn accelerometer and self-report, and participants were divided into short (<7 h/night), mid-range (7–9 h/night) and long (≥9 h/night) sleepers. Participants underwent extensive cognitive testing covering three domains: (1) memory, (2) executive function, and (3) attention and information processing. Results: Greater difficulties in waking up too early in the morning were associated with poorer executive function measured with Spatial Working Memory (SWM) test (p = 0.005). Additionally, nonrestorative sleep was associated with poorer executive function measured with Trail Making Test, B–A, (p = 0.036) and borderline significantly with lower SWM (p = 0.056). Compared to mid-range sleepers, long sleepers tended to have poorer cognitive function (all memory function tests and SWM), but the associations were not statistically significant due to small number of long sleepers. Conclusions: Subjective sleep difficulties may be linked to poorer executive function in a relatively healthy population of older workers in their 60 s. Thus, promoting good sleep quality may translate into better cognitive health in late mid-life.
KW - Accelerometer
KW - Cognitive function
KW - Sleep difficulties
KW - Sleep duration
KW - Sleep quality
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UR - http://www.scopus.com/inward/citedby.url?scp=85078714394&partnerID=8YFLogxK
U2 - 10.1016/j.sleep.2019.08.024
DO - 10.1016/j.sleep.2019.08.024
M3 - Article
C2 - 32028225
AN - SCOPUS:85078714394
SN - 1389-9457
VL - 68
SP - 42
EP - 49
JO - Sleep Medicine
JF - Sleep Medicine
ER -