Association of traditional cardiovascular risk factors with coronary plaque sub-types assessed by 64-slice computed tomography angiography in a large cohort of asymptomatic subjects

Juan J. Rivera, Khurram Nasir, Pedro R. Cox, Eue Keun Choi, Yeonyee Yoon, Iksung Cho, Eun Ju Chun, Sang Il Choi, Roger S Blumenthal, Hyuk Jae Chang

Research output: Contribution to journalArticle

Abstract

Objective: Although prior studies have shown that traditional cardiovascular (CV) risk factors are associated with the burden of coronary atherosclerosis, less is known about the relationship of risk factors with coronary plaque sub-types. Coronary computed tomography angiography (CCTA) allows an assessment of both, total disease burden and plaque characteristics. In this study, we investigate the relationship between traditional CV risk factors and the presence and extent of coronary plaque sub-types in a large group of asymptomatic individuals. Methods: The study population consisted of 1015 asymptomatic Korean subjects (53 ± 10 years; 64% were males) free of known CV disease who underwent 64-slice CCTA as part of a health screening evaluation. We analyzed plaque characteristics on a per-segment basis according to the modified American Heart Association classification. Plaques in which calcified tissue occupied more than 50% of the plaque area were classified as calcified (CAP),

Original languageEnglish (US)
Pages (from-to)451-457
Number of pages7
JournalAtherosclerosis
Volume206
Issue number2
DOIs
StatePublished - Oct 2009

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Coronary Artery Disease
Cardiovascular Diseases
Health
Population
Computed Tomography Angiography

Keywords

  • Asymptomatic individuals
  • Coronary computed tomography angiography
  • Coronary plaque
  • Plaque morphology

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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Association of traditional cardiovascular risk factors with coronary plaque sub-types assessed by 64-slice computed tomography angiography in a large cohort of asymptomatic subjects. / Rivera, Juan J.; Nasir, Khurram; Cox, Pedro R.; Choi, Eue Keun; Yoon, Yeonyee; Cho, Iksung; Chun, Eun Ju; Choi, Sang Il; Blumenthal, Roger S; Chang, Hyuk Jae.

In: Atherosclerosis, Vol. 206, No. 2, 10.2009, p. 451-457.

Research output: Contribution to journalArticle

Rivera, Juan J. ; Nasir, Khurram ; Cox, Pedro R. ; Choi, Eue Keun ; Yoon, Yeonyee ; Cho, Iksung ; Chun, Eun Ju ; Choi, Sang Il ; Blumenthal, Roger S ; Chang, Hyuk Jae. / Association of traditional cardiovascular risk factors with coronary plaque sub-types assessed by 64-slice computed tomography angiography in a large cohort of asymptomatic subjects. In: Atherosclerosis. 2009 ; Vol. 206, No. 2. pp. 451-457.
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AU - Choi, Eue Keun

AU - Yoon, Yeonyee

AU - Cho, Iksung

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AU - Blumenthal, Roger S

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