Association of SPOP Mutations with Outcomes in Men with De Novo Metastatic Castration-sensitive Prostate Cancer

Umang Swami, Pedro Isaacsson Velho, Roberto Nussenzveig, Jonathan Chipman, Victor Sacristan Santos, Stephanie Erickson, Divya Dharmaraj, Ajjai Shivaram Alva, Ulka N. Vaishampayan, John Esther, Andrew W. Hahn, Benjamin Louis Maughan, Emmanuel S. Antonarakis, Neeraj Agarwal

Research output: Contribution to journalArticlepeer-review

Abstract

Presence of tumor mutation in speckle-type pox virus and zinc finger protein (SPOP) gene was associated with improved survival outcomes in men with de novo metastatic castration-sensitive prostate cancer receiving standard androgen deprivation therapy.

Original languageEnglish (US)
Pages (from-to)652-656
Number of pages5
JournalEuropean Urology
Volume78
Issue number5
DOIs
StatePublished - Nov 2020

Keywords

  • Androgen deprivation therapy
  • Metastatic hormone-sensitive prostate cancer
  • Overall survival
  • Progression-free survival
  • SPOP

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Association of SPOP Mutations with Outcomes in Men with De Novo Metastatic Castration-sensitive Prostate Cancer'. Together they form a unique fingerprint.

Cite this